Rare disease
Von Willebrand Disease Type 3
Clinical trials recruiting in Australia for Von Willebrand Disease Type 3, a rare disease, as the public registries list them.
Also called: Hereditary pseudohaemophilia; Hereditary von Willebrand disease; Von Willebrand disease; Von Willebrand disorder; Von Willebrand's factor deficiency
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At a glance
4 trials recruiting in Australia
31 trials recruiting overseas
1-5 / 10 000 (Point prevalence, Worldwide, Validated) prevalence
All ages age of onset
11 October 2026 date last checked
Trials in Australia
This Australian count is likely to be on the low side. It counts the trials this site files under this condition; the registry’s own search is broader and also returns closely related conditions, some of which have their own page here. If you are searching widely, check the registry as well — every trial below links to its own record.
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Recruiting Phase 2
Phase 2 study for people with Von Willebrand Disease Type 3
Where- Royal Brisbane & Women's Hospital, Queensland Haemophilia Centre, Herston (QLD) — Recruiting
Who can join Age 12 Years to 60 Years. Sex Anyone, regardless of sex. Healthy volunteers Accepted.Sponsor Vega Therapeutics, IncTimelineStarted 16 March 2023 Today 16 October 2026 Estimated completion 1 December 2029NCT05776069 · Checked 11 October 2026
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Recruiting Not a phased study
Study for people with Von Willebrand Disease Type 3
Where- Fiona Stanley Hospital, Murdoch (WA) — Recruiting
- Royal Prince Alfred Hospital, Camperdown (NSW) — Recruiting
- The Alfred Hospital, Melbourne (VIC) — Recruiting
Who can join Age 16 Years and over. Sex Anyone, regardless of sex. Healthy volunteers Not accepted.Sponsor Hemab ApSTimelineStarted 30 August 2024 Today 16 October 2026 Estimated completion 1 December 2026NCT06610201 · Checked 11 October 2026
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Recruiting Phase 2
Phase 2 study for people with Von Willebrand Disease Type 3
Where- Fiona Stanley Hospital, Murdoch (WA) — Not yet recruiting
- Royal Prince Alfred Hospital, Camperdown (NSW) — Recruiting
- The Alfred Hospital, Melbourne (VIC) — Recruiting
Who can join Age 16 Years to 69 Years. Sex Anyone, regardless of sex. Healthy volunteers Not accepted.Sponsor Hemab ApSTimelineStarted 6 February 2025 Today 16 October 2026 Estimated completion 1 July 2027NCT06754852 · Checked 11 October 2026
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Recruiting Phase 3
Phase 3 study for people with Von Willebrand Disease Type 3
Where- Royal Prince Alfred Hospital, Institute of Haematology, Sydney (NSW) — Recruiting
- Royal Brisbane & Women's Hospital (RBWH), Queensland Haemophilia Centre, Brisbane (QLD) — Recruiting
- The Alfred Hospital (Alfred Health),Monash University, Melbourne (VIC) — Recruiting
Who can join Age 12 Years to 75 Years. Sex Anyone, regardless of sex. Healthy volunteers Not accepted.Sponsor Vega Therapeutics, IncTimelineStarted 15 October 2025 Today 16 October 2026 Estimated completion 1 October 2028NCT07115004 · Checked 11 October 2026
Trials overseas
31 trials for this disease are open to new participants outside Australia, as ClinicalTrials.gov listed them on 11 October 2026. Voxsanity does not publish a page for any of them; the searches below reach them at the registry.
These overseas counts are likely too high. They come from the registry’s own search, which expands a condition name to related conditions, so some of the trials counted are for a different disease in the same family.
Search ClinicalTrials.gov Search the WHO registry portal Joining a trial overseas
Trials not shown here
Some Australian trials are registered only on the Australian New Zealand Clinical Trials Registry and are not shown here. Search them at Australian Clinical Trials.
Key facts
Orphadata Science: Free access data from Orphanet. © INSERM 1999. Available on https://www.orphadata.com. Used under CC BY 4.0. Source: Orphanet / Orphadata (orphadata.com).
About Von Willebrand Disease Type 3
The text below is reproduced exactly as its source published it. It has not been edited, shortened or rewritten.
Von Willebrand disease is a bleeding disorder that slows the blood clotting process, causing prolonged bleeding after an injury. People with this condition often experience easy bruising, long-lasting nosebleeds, and excessive bleeding or oozing following an injury, surgery, or dental work. Mild forms of von Willebrand disease may become apparent only when abnormal bleeding occurs following surgery or a serious injury. People with this condition who have menstrual periods typically have heavy or prolonged bleeding during menstruation (menorrhagia), and some may also experience reproductive tract bleeding during pregnancy and childbirth. In severe cases of von Willebrand disease, heavy bleeding occurs after minor trauma or even in the absence of injury (spontaneous bleeding). Symptoms of von Willebrand disease may change over time. Increased age, pregnancy, exercise, and stress may cause bleeding symptoms to become less frequent. Von Willebrand disease is divided into three types. Type 1 has one subtype (1C), and type 2 is divided into four subtypes (2A, 2B, 2M, and 2N). Type 1 is the most common of the three types, accounting for 75 percent of affected individuals. Type 1 is typically mild, but some people are severely affected. Type 2 accounts for about 15 percent of cases. This type is usually of intermediate severity. Type 3 is the rarest form of the condition, accounting for about 5 percent of affected individuals, and is usually the most severe. Another form of the disorder, acquired von Willebrand syndrome, is not caused by inherited gene variants (also called mutations). Acquired von Willebrand syndrome is typically seen in people with other disorders, such as diseases that affect bone marrow or immune cell function. This rare form of the condition is characterized by abnormal bleeding into the skin and other soft tissues, usually beginning in adulthood.
US source; availability in Australia may differ.
Source: MedlinePlus Genetics (medlineplus.gov), public domain (U.S. National Library of Medicine). Read the full source.
Sources and dates
- ClinicalTrials.gov – trial records, statuses and site lists
- MedlinePlus – the About text above, reproduced exactly
- Orphanet / Orphadata – prevalence, age of onset, inheritance, genes and alternative names, used under CC BY 4.0
- ClinicalTrials.gov processing date: 14 September 2026.
- This page last checked by Voxsanity: 11 October 2026.
Voxsanity reformats data from public registries into this layout. It does not edit, interpret or add to what the registry published.
Not medical advice.
Individual trial records are refreshed on a rolling basis rather than all at once, so a record may be up to several weeks old. Each trial page and trial card shows the date its own record was last synced. Where a record has lagged, its status, sites and enrolment can differ from the current registry state in either direction, so check the registry link on the trial page before acting on them.
Orphanet citation
Orphadata Science: Free access data from Orphanet. © INSERM 1999. Available on https://www.orphadata.com. Used under CC BY 4.0. Source: Orphanet / Orphadata (orphadata.com). Accessed 20 September 2026.
Von Willebrand Disease Type 3 is one of the rare diseases tracked on the Voxsanity rare disease hub, where you can compare it with every other rare condition we follow and filter trials by country.
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