Phase 3 Breast Cancer Trial, Terminated NCT00373113 Sponsor: Pfizer Condition: Breast Cancer
Back to Breast Cancer

Trial results

AI generated results summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

According to the results reported on ClinicalTrials.gov, this trial compared two treatments — sunitinib and capecitabine — in people with a specific type of cancer. A total of 238 people were assigned to the sunitinib group and 244 to the capecitabine group, making 482 participants in all. The trial's main goal was to measure "progression-free survival" — that is, how long participants went before their cancer showed signs of growing or spreading, or before they died from any cause, whichever came first. The reported data shows that, for the main measure, participants in the sunitinib group had a median progression-free survival of 2.8 months, compared with 4.2 months in the capecitabine group. (Median means the midpoint — half the participants in each group had a result above this figure and half below.) The reported data also shows that the time until the cancer first showed signs of growing was 2.8 months for sunitinib and 4.2 months for capecitabine. When looking at how many participants showed a measurable shrinkage in their tumours, 27 people in the sunitinib group and 40 people in the capecitabine group met this measure. Among those who did show a response, that response lasted a reported 6.9 months on average in the sunitinib group and 9.3 months in the capecitabine group. The average overall survival — time from the start of the trial until death from any cause — was reported as 15.3 months for sunitinib and 16.9 months for capecitabine. The time-to-tumour-response figures were not reported in the submitted data. These are the results as reported to ClinicalTrials.gov. They are not medical advice — always discuss what they mean for you with your doctor.

These are the results as reported to ClinicalTrials.gov, not medical advice. Verify independently with the trial site and discuss what they mean for you with your doctor.

Phase 3 Breast Cancer Trial, Terminated

NCT00373113
Terminated Phase 3 🇦🇺 Australian site

voxsanity.com.au · Eligibility summary from public government registries · 18 August 2026 · not medical advice

Who may and may not be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who may be able to join

  • You have been diagnosed with a type of breast cancer called breast adenocarcinoma
  • You have already been treated with two specific types of chemotherapy drugs — an anthracycline and a taxane — either together or one after the other, whether that was before surgery, after surgery, or for advanced disease, with no more than one chemotherapy treatment course given for advanced disease

Who may not be able to join

Each point below is a reason the trial team may not be able to accept someone. It is not a list of requirements to meet.

  • You have received chemotherapy for advanced or metastatic breast cancer that went beyond treatments containing anthracyclines and taxanes, or you have had multiple separate courses of anthracycline or taxane treatments
  • You have previously been treated with a drug called capecitabine (also known by the brand name Xeloda) at any point

Important: Always verify eligibility with the trial site directly before applying."

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 27 July 2026

Trial contact details on record

Principal Investigator: Pfizer CT.gov Call Center, Pfizer

Australian sites

Pfizer Investigational Site, Darlinghurst, New South Wales
Pfizer Investigational Site, Herston, Queensland
Pfizer Investigational Site, Adelaide, South Australia
Pfizer Investigational Site, Heidelberg, Victoria
Pfizer Investigational Site, Parkville, Victoria
Pfizer Investigational Site, Perth, Western Australia

This trial is not accepting new participants. These are the contact details ClinicalTrials.gov holds for it, kept here for reference. They are not an invitation to enrol, and the sites listed may no longer be running this trial.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Terminated
Phase
Phase 3
Sponsor
Registry
ClinicalTrials.gov
Start date
1 November 2006
Est. completion
1 October 2009

Where this trial was run

🇦🇷 Argentina 🇦🇺 Australia 🇧🇷 Brazil 🇧🇬 Bulgaria 🇨🇦 Canada 🇨🇱 Chile 🇨🇴 Colombia 🇫🇷 France 🇩🇪 Germany Hong Kong 🇮🇳 India 🇮🇹 Italy 🇯🇵 Japan 🇲🇽 Mexico 🇵🇪 Peru 🇵🇭 Philippines 🇸🇬 Singapore 🇿🇦 South Africa 🇰🇷 South Korea 🇪🇸 Spain 🇹🇼 Taiwan Turkey (Türkiye) 🇬🇧 United Kingdom

These are the locations recorded on the registry, including 6 in Australia. They are a historical record: this trial is not enrolling, so they are not places you can join it.

Primary endpoints

Progression-Free Survival (PFS)

Other options

Expanded access pathways

This trial is not enrolling. Other access pathways exist in general: in Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients. Whether it applies to any treatment studied here is a question for your doctor — nothing on this page says it does.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov