Phase 3 Alzheimer's Disease Trial, Completed NCT00416078 Sponsor: US Department of Veterans Affairs Condition: Alzheimer's Disease
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Trial results

AI generated results summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

According to the results reported on ClinicalTrials.gov, this trial involved 53 caregivers of people with memory or behavioural problems. Twenty-nine caregivers were assigned to receive support through a website, and 24 received support through phone calls. The trial was measuring several things related to the caregiver experience: how much strain or burden the caregivers felt, their own mood and depressive feelings, how often the person they cared for showed difficult behaviours, how distressed the caregiver felt in response to those behaviours, and how well the person being cared for was taking their prescribed medicines. By the end of the study, 18 people in the website group and 16 in the phone calls group had completed the trial. The reported data shows the following scores at the follow-up point. For caregiver burden (measured on a scale of 12 to 60, where higher means more burden), the website group scored 32.52 and the phone calls group scored 27.55. For difficult patient behaviours (scored 0 to 96, higher meaning more frequent), the website group scored 33.28 and the phone calls group scored 34.75. For caregiver distress about those behaviours (also 0 to 96), the website group scored 20.23 and the phone calls group scored 20.08. For caregiver depression symptoms (scored 0 to 63, higher meaning more symptoms), the website group scored 8.61 and the phone calls group scored 9.43. For caregiver-reported medicine-taking by the patient (scored 1 to 5, higher meaning better), the website group scored 5.08 and the phone calls group scored 3.94. The reported data also shows that 2 people in the website group and 3 in the phone calls group moved into assisted living or a nursing home during the 12-month period. It is worth noting that these numbers reflect scores at a single point in time as reported, and the trial's starting (baseline) scores were also recorded — however, the data as submitted does not separately detail the calculated change figures in a way that allows a straightforward before-and-after comparison to be described here. These are the results as reported to ClinicalTrials.gov. They are not medical advice — always discuss what they mean for you with your doctor.

These are the results as reported to ClinicalTrials.gov, not medical advice. Verify independently with the trial site and discuss what they mean for you with your doctor.

Phase 3 Alzheimer's Disease Trial, Completed

NCT00416078
Completed Phase 3

voxsanity.com.au · Eligibility summary from public government registries · 18 August 2026 · not medical advice

Who may and may not be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who may be able to join

  • The patient lives in the community (not in a care home or facility) and is able to get around.
  • The patient has been diagnosed with Alzheimer's disease.
  • The patient is between 50 and 95 years old.
  • The caregiver is between 18 and 90 years old.
  • The patient is currently receiving treatment for Alzheimer's disease.
  • Both the patient and caregiver live within 2 hours of Los Angeles.
  • The caregiver has access to the internet at home.
  • The patient has regular, close contact with their caregiver.

Who may not be able to join

Each point below is a reason the trial team may not be able to accept someone. It is not a list of requirements to meet.

  • The patient lives in a residential care setting, such as a nursing home or assisted living facility.
  • The patient has no family contact.
  • The patient or caregiver has a sudden illness or an ongoing long-term health condition (confirm with trial site).
  • The patient or caregiver is planning to move away from the area within the next year.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 17 August 2026

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Completed
Phase
Phase 3
Registry
ClinicalTrials.gov
Start date
1 August 2007
Est. completion
1 June 2012

Where this trial was run

🇺🇸 United States

These are the locations recorded on the registry, and they are a historical record: this trial is not enrolling, so they are not places you can join it.

Primary endpoints

Change in Caregiver Burden From Baseline; Change in Frequency of Patient Problematic Behavioral Patterns From Baseline; Change in Caregiver Negative Reactions to Problematic Behavioral Patterns From Baseline; Change in Caregiver Depression From Baseline

Other options

Expanded access pathways

This trial is not enrolling. Other access pathways exist in general: in Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients. Whether it applies to any treatment studied here is a question for your doctor — nothing on this page says it does.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 17 August 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov