Phase 3 Sleep Disorders Trial, Terminated NCT00519532 Sponsor: UCB Pharma Condition: Sleep Disorders
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Trial results

AI generated results summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

According to the results reported on ClinicalTrials.gov, this trial enrolled 84 people with Parkinson's disease who received a treatment called rotigotine (delivered as a skin patch). Of the 84 who started, 66 completed the trial and 18 did not finish. The trial was measuring two main things: changes in motor (movement-related) symptoms using a standard Parkinson's rating tool called the UPDRS III, and changes in sleep quality using a Parkinson's-specific sleep questionnaire called the PDSS. Both of these were assessed after 13 weeks of treatment. The reported data shows that, on average, participants' UPDRS III scores — where higher numbers indicate more severe movement problems — changed by minus 5.8 units from the starting point, meaning scores were lower at week 13 than at the beginning. The sleep scale (PDSS) scores also changed by minus 5.8 units on average; on this scale, lower scores indicate fewer sleep-related difficulties. It is worth noting that the two measures used different starting ("baseline") reference points, so they are not directly comparable to each other. The reported data also shows results for two secondary (additional) measures. Scores for nighttime movement difficulties, muscle stiffness, and cramps (measured on a scale of 0–4) changed by an average of minus 1.5 units. The average number of times participants woke during the night to go to the toilet changed by minus 0.4 occasions. These are the results as reported to ClinicalTrials.gov. They are not medical advice — always discuss what they mean for you with your doctor.

These are the results as reported to ClinicalTrials.gov, not medical advice. Verify independently with the trial site and discuss what they mean for you with your doctor.

Phase 3 Sleep Disorders Trial, Terminated

NCT00519532
Terminated Phase 3 🇦🇺 Australian site

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You must have already completed a previous clinical trial called SP889.

Who may not be able to join:

  • You are currently experiencing a serious negative health reaction that is believed to be caused by the medication used in the previous trial (SP889).

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 27 July 2026
Phase 3: approximately ~65% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: UCB Clinical Trial Call Center, +1 877 822 9493 (UCB)

Australian sites

, Concord,

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

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Trial details

Status
Terminated
Phase
Phase 3
Sponsor
UCB Pharma
Registry
ClinicalTrials.gov
Start date
1 July 2007
Est. completion
1 May 2009

Where this trial is recruiting

🇦🇺 Australia 🇫🇮 Finland 🇩🇪 Germany 🇭🇺 Hungary 🇮🇹 Italy 🇳🇿 New Zealand 🇵🇱 Poland 🇿🇦 South Africa 🇪🇸 Spain 🇬🇧 United Kingdom 🇺🇸 United States

1 site(s) in Australia. Confirm current status and contact details directly with the trial site.

Primary endpoints

Change From Baseline in UPDRS III Score at Week 13 (End of Maintenance); Change From Baseline in Parkinson Disease Sleep Scale (PDSS) at Week 13 (End of Maintenance)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov