Trial results
AI generated results summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
According to the results reported on ClinicalTrials.gov, this trial involved 19 people in total — 8 in the active rTMS (repetitive transcranial magnetic stimulation, a type of brain stimulation) group and 11 in the sham (inactive/pretend) rTMS group. One person in the active group did not complete the trial, while all 11 in the sham group finished. The trial was measuring pain intensity and pain unpleasantness in participants, as well as depression levels and any unwanted events that occurred during the study. Measurements were taken at the start, each week during three weeks of treatment, and one week after treatment ended. The reported data shows that for the main measurement — pain intensity, scored on a 20-point scale where lower means less pain — the sham group started at an average of 13.18 and ended at 8.60 one week after treatment, while the active rTMS group started at 14.43 and ended at 10.50. For pain unpleasantness (also a 20-point scale), the sham group went from 9.91 at the start to 7.60 at the end, and the active group went from 12.57 to 9.83. For depression (scored on a scale of 0–50), the sham group went from 14.64 to 7.45, and the active group went from 14.71 to 8.67. Both groups showed a downward trend across all three measures over the course of the study. The reported data also shows that 36 unwanted events were recorded in the active rTMS group and 35 in the sham group over the course of the trial. No further detail about the nature of these events was included in the submitted results data. These are the results as reported to ClinicalTrials.gov. They are not medical advice — always discuss what they mean for you with your doctor.
View full results on ClinicalTrials.gov ↗ · Read the linked publication on PubMed (PMID 17502802) ↗
These are the results as reported to ClinicalTrials.gov, not medical advice. Verify independently with the trial site and discuss what they mean for you with your doctor.
Phase 2 Depression and Anxiety Trial, Completed
voxsanity.com.au · Eligibility summary from public government registries · 18 August 2026 · not medical advice
Who may and may not be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who may be able to join
- You have been diagnosed with long-term, widespread muscle or body pain lasting at least 3 months, affecting both the upper and lower body, both sides of the body, and at least one central area like the head, neck, spine, or back.
- You are willing to keep taking the same medications without changing them for the 8 weeks before the study starts and throughout the 6-week treatment phase.
- You are willing to be randomly assigned to a treatment group and are able to attend the required treatment sessions.
- If you are currently receiving talk therapy or counselling, it has been ongoing for at least 3 months and you are willing to keep it at the same level throughout the study.
Who may not be able to join
Each point below is a reason the trial team may not be able to accept someone. It is not a list of requirements to meet.
- You are unable to stay on the same medications at the same doses for 8 weeks before and during the study.
- You have another health condition that also causes significant pain, such as diabetic nerve pain, lupus, rheumatoid arthritis, or severe joint disease.
- You have any condition that could increase the risk of having a seizure during the treatment (confirm with trial site).
- You have a personal or family history of seizures or epilepsy.
- You have previously received the type of brain stimulation treatment used in this study (TMS).
- You are currently involved in a legal case or disability claim related to your pain condition or depression.
- You are currently taking certain medications that can lower the seizure threshold, such as bupropion (confirm with trial site for full list).
- You have metal implants in your body, such as a pacemaker, aneurysm clips, or nerve stimulators, that would make an MRI or the brain stimulation treatment unsafe.
- You have a history of a serious head injury with more than 15 minutes of unconsciousness, brain surgery, or lithium poisoning.
- You have a history of bipolar disorder, schizophrenia, obsessive-compulsive disorder, panic disorder, or post-traumatic stress disorder.
- You are currently misusing or dependent on alcohol or drugs.
- You are currently having active thoughts of suicide or have a plan to harm yourself.
- You have severe fear of enclosed spaces that would prevent you from having an MRI scan.
- You have severe depression with psychotic symptoms, or a current depressive episode that has lasted longer than 5 years.
- You are currently pregnant.
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
If you need support right now
This page includes language about suicide and self-harm, because that is how the trial's eligibility criteria are written. If reading it has been hard, you do not have to keep going. The services below are free, confidential, and answered by people trained for exactly this.
If you or someone else is in immediate danger, call 000.
- Lifeline — 24/7 crisis support: 13 11 14
- Suicide Call Back Service — 24/7 counselling: 1300 659 467
- 13YARN — 24/7, for Aboriginal and Torres Strait Islander people: 13 92 76
- Beyond Blue — 24/7 mental health support: 1300 22 4636
- Emergency: 000
Outside Australia? The numbers above are Australian and will not work from overseas. Find a Helpline is a free directory of crisis lines in over 130 countries, run by ThroughLine with the International Association for Suicide Prevention. If you are in immediate danger, call your local emergency number.
Voxsanity is not a crisis service, and nothing on this page is medical advice. More Australian services are listed on our support lines page.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial was run
These are the locations recorded on the registry, and they are a historical record: this trial is not enrolling, so they are not places you can join it.
Primary endpoints
Gracely Box Intensity Rating Scale
Other options
Data last synced from ClinicalTrials.gov: 18 August 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.