Phase 3 Alzheimer's Disease Trial, Terminated NCT02245568 Sponsor: TauRx Therapeutics Ltd Condition: Alzheimer's Disease
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Trial results

AI generated results summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

According to the results reported on ClinicalTrials.gov, this trial (NCT02245568) enrolled 913 participants, all of whom received the study treatment LMTM at doses ranging from 100 to 300 mg per day. Of those who started the trial, 60 participants completed it, while 853 did not complete their participation. The trial was measuring adverse events — that is, any new or worsening health problems that occurred after participants started taking the study treatment, including notable changes in laboratory tests, vital signs, or heart monitoring results. The reported data shows that the primary outcome being tracked was the number of participants who experienced serious or non-serious adverse events during the study. According to the results reported on ClinicalTrials.gov, 734 out of 913 participants were recorded as having at least one such adverse event. No secondary outcome measures appear to have been reported in the data submitted to ClinicalTrials.gov for this trial. These are the results as reported to ClinicalTrials.gov. They are not medical advice — always discuss what they mean for you with your doctor.

These are the results as reported to ClinicalTrials.gov, not medical advice. Verify independently with the trial site and discuss what they mean for you with your doctor.

Phase 3 Alzheimer's Disease Trial, Terminated

NCT02245568
Terminated Phase 3 🇦🇺 Australian site

voxsanity.com.au · Eligibility summary from public government registries · 18 August 2026 · not medical advice

Who may and may not be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who may be able to join

  • You must have already completed participation in one of three specific earlier TauRx research studies (TRx-237-005, TRx-237-008, or TRx-237-015) for dementia or probable Alzheimer's disease, including a 4-week follow-up visit at the end of that study
  • Alternatively, you must have already completed participation up to Week 52 in a specific earlier TauRx study (TRx-237-007) for a condition called behavioural variant frontotemporal dementia (a type of brain condition affecting behaviour and personality)
  • If you are a woman who could become pregnant, you must be willing to use reliable contraception or practice complete abstinence throughout the study
  • You (or a legal representative acting on your behalf, if needed) must be able to read, understand, and sign a written consent form agreeing to take part
  • You must have an adult caregiver who consents to be involved, can speak the language used at the study site, spends at least 1 hour a day with you at least 3 days a week, is willing to come with you to every study visit, and can confirm you are taking the study medication as directed
  • You must be able to follow the study procedures throughout the trial

Who may not be able to join

Each point below is a reason the trial team may not be able to accept someone. It is not a list of requirements to meet.

  • People who have a history of difficulty swallowing
  • People who are currently pregnant or breastfeeding
  • People who have significant abnormal results from lab tests, heart monitoring, or scans, or who have developed a serious illness that the lead doctor believes makes the risks of joining the trial too high
  • People who are currently in another clinical trial or plan to join one during this study
  • In Germany specifically: people who are required to live in a full-time care or assisted living facility, or whose ability to freely choose to participate may be unduly influenced (confirm with trial site)

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 13 August 2026

Trial contact details on record

Australian sites

Frontotemporal Research Group, Camperdown, New South Wales
Division of Rehabilitation and Aged Care, Hornsby, New South Wales
Southern Neurology Pty Limited, Kogarah, New South Wales
Discipline of Psychiatry, University of Queensland, Herston, Queensland
Royal Adelaide Hospital Memory Trials Centre, Adelaide, South Australia
Box Hill Hospital, Box Hill, Victoria
Medical and Cognitive Research Unit, Austin Health Heidelberg Repatriation Hospital, Heidelberg West, Victoria
McCusker Alzheimer's Research Foundation Inc, Nedlands, Western Australia
Neurodegenerative Disorders Research Pty Ltd, Subiaco, Western Australia

This trial is not accepting new participants. These are the contact details ClinicalTrials.gov holds for it, kept here for reference. They are not an invitation to enrol, and the sites listed may no longer be running this trial.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Terminated
Phase
Phase 3
Sponsor
TauRx Therapeutics Ltd
Registry
ClinicalTrials.gov
Start date
1 August 2014
Est. completion
1 May 2017

Where this trial was run

🇦🇺 Australia 🇧🇪 Belgium 🇨🇦 Canada 🇭🇷 Croatia 🇫🇮 Finland 🇫🇷 France 🇩🇪 Germany 🇲🇾 Malaysia 🇳🇱 Netherlands 🇷🇴 Romania 🇷🇺 Russia 🇸🇬 Singapore 🇰🇷 South Korea 🇪🇸 Spain 🇹🇼 Taiwan 🇬🇧 United Kingdom 🇺🇸 United States

These are the locations recorded on the registry, including 9 in Australia. They are a historical record: this trial is not enrolling, so they are not places you can join it.

Primary endpoints

Number of Participants With Serious or Non-serious Adverse Events

Other options

Expanded access pathways

This trial is not enrolling. Other access pathways exist in general: in Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients. Whether it applies to any treatment studied here is a question for your doctor — nothing on this page says it does.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 13 August 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov