Rheumatoid Arthritis Trial, Recruiting NCT02327884 Sponsor: National Institute of Dental and Craniofacial Research (NIDCR) Condition: Rheumatoid Arthritis
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Rheumatoid Arthritis Trial, Recruiting

NCT02327884
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People older than 4 years of age who have, or are suspected of having, a disease or condition affecting the salivary glands, or who are a family member of someone with such a condition.
  • People aged 18 or older who have active hepatitis (with or without dry mouth or dry eye symptoms), or who are receiving a type of cancer treatment called an immune checkpoint inhibitor for oral cancer.
  • People aged 18 or older who are in good health and are willing to have blood, urine, saliva, or tissue samples collected for research.

Who may not be able to join:

  • People who are not able to give their own consent, and where a parent or guardian is also unable to give consent on their behalf.
  • NIH employees who report directly to the lead researcher running the trial.
  • People with a serious existing medical condition or other circumstances that could make it difficult to complete the study, such as currently receiving chemotherapy or having a bleeding disorder (note: for people receiving immune checkpoint inhibitor treatment for oral cancer, having oral cancer itself will not count as a reason to be excluded).
  • People receiving immune checkpoint inhibitor treatment who are unable to tolerate certain study procedures — such as salivary gland biopsies, saliva collection, or mouth examinations — as determined by the lead researcher.
  • Healthy volunteers who are pregnant.
  • Healthy volunteers who have dry mouth or dry eye symptoms.
  • Healthy volunteers who have HIV, hepatitis B, or hepatitis C.
  • Healthy volunteers who have a long-term (chronic) medical illness, unless it is high blood pressure or high cholesterol that is well-managed.
  • Healthy volunteers who regularly take medications, with the exception of oral contraceptives, hormone replacement therapy, aspirin, blood pressure medications, or cholesterol-lowering medications.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 12 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Margaret E Beach, P.A.-C, National Institute of Dental and Craniofacial Research (NIDCR)

Phone: (301) 594-3097

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
National Institute of Dental and Craniofacial Research (NIDCR)
Registry
ClinicalTrials.gov
Start date
3 April 2015
Est. completion
1 April 2032

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

hypothesis generating

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 12 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov