Rheumatoid Arthritis

Who might be able to join this trial: - You have been diagnosed with a type of early, not fully defined joint inflammation called "undifferentiated arthritis." - You have visible joint swelling (synovitis) in two or more joints. - You meet at least one, but no more than three, of the standard medical checklist items us...

**Who might be able to join this trial:** - You have been diagnosed with rheumatoid arthritis (RA) for at least 3 months before starting the study - You have never taken methotrexate (MTX) before, or have taken no more than 3 weekly doses of it for RA at any time - Your RA is currently active, meaning you have at leas...

**Who might be able to join this trial:** - You have been diagnosed with rheumatoid arthritis (RA) for at least 3 months before the screening visit - You have been taking methotrexate (a common RA medication) at a dose of at least 15 mg per week for at least 3 months, and your dose has stayed the same for at least 4 we...

**Who might be able to join this trial:** - You must have already taken part in a separate, randomised clinical trial of CP-690,550 (also called tofacitinib) for rheumatoid arthritis that qualifies you for this study - If you are currently taking part in a specific related study (A3921024), you must have been taking CP...

**Who might be able to join this trial:** - You are 18 years of age or older - You have been diagnosed with rheumatoid arthritis (RA) for at least 6 months - You are receiving treatment as an outpatient (not staying in hospital) - You have been taking methotrexate for at least 12 weeks, have tolerated it, and have been...

Who might be able to join this trial: - You have been diagnosed with Rheumatoid Arthritis by a doctor - You rate your overall disease condition as at least 20 out of 100 on a simple sliding scale measurement - You are willing and able to stop taking all biological treatments and most other arthritis medications, except...

**Who might be able to join this trial:** - You have signed and given written consent to take part in the study. - Women must not be pregnant, breastfeeding, or likely to become pregnant during the study. - You must have previously taken part in one of two specific earlier studies (called NCT00689728 or NCT00785928)....

Who might be able to join this trial: - You are an adult who has been diagnosed with moderate to severe rheumatoid arthritis - You are taking methotrexate at a steady, unchanged dose - You have tried TNF inhibitor medications (a type of treatment that targets inflammation) but they have not worked well enough for you...

Who might be able to join this trial: - You have been diagnosed with rheumatoid arthritis (a condition where the immune system attacks the joints) for at least 3 months before the screening visit. - You have been taking methotrexate (a common arthritis medication) at a dose of at least 15 mg per week for at least 3 mon...

Who might be able to join this trial: - You must be 18 years of age or older. - You must have been diagnosed with rheumatoid arthritis for 2 years or less. - Your rheumatoid arthritis must be considered moderately to highly active, based on a standard disease activity measurement called the DAS28 score (confirm with tr...

Who might be able to join this trial: - You have active joint swelling and inflammation in at least 2 joints (one of which must be a small joint, such as in the hand or foot), and this has been present for at least 8 weeks before your initial assessment - Your joint symptoms started no more than 2 years before your ini...

**Who might be able to join this trial:** - You are 18 years of age or older - You have been diagnosed with rheumatoid arthritis (RA) for at least 6 months, based on recognised medical guidelines - You have at least 4 swollen joints and at least 4 tender joints at the time of your first assessment and at the start of t...

**Who might be able to join this trial:** - You have been diagnosed with rheumatoid arthritis (RA), and you were at least 16 years old when you were diagnosed - You are currently taking the medication methotrexate - You have 6 or more swollen joints AND 6 or more tender or painful joints, plus at least one of two spec...

**Who might be able to join this trial:** - You were diagnosed with Rheumatoid Arthritis (RA) as an adult, and your diagnosis was made less than 1 year ago - Your blood tests show positive results for certain markers linked to RA (called Rheumatoid Factor and/or anti-CCP antibodies) - Your RA is currently active (meani...

Who might be able to join this trial: - People who have been diagnosed with adult-onset Rheumatoid Arthritis (RA) according to the 2010 classification guidelines set by major rheumatology organisations - People whose RA is moderately to severely active, meaning at least 6 out of 68 joints are tender and at least 6 out...

Who might be able to join this trial: - You must have already completed participation in one of two specific related studies (called CNTO136ARA3002 or CNTO136ARA3003). - You must be willing to sign a consent form showing you understand what the study involves and agree to take part. - You must be willing to sign a sepa...

**Who might be able to join this trial:** - You have been diagnosed with rheumatoid arthritis (a condition causing joint inflammation) for at least 4 months, based on specific medical guidelines - You have at least 6 painful and 6 swollen joints (out of a standard set checked by a doctor) at two separate check-in appoi...

Who might be able to join this trial: - You are a man or woman aged 18 or older. - You have been diagnosed with rheumatoid arthritis (RA) for at least 3 months. - You have been taking a standard RA medication (such as methotrexate, sulfasalazine, hydroxychloroquine, chloroquine, or leflunomide) for at least 3 months, a...

Who might be able to join this trial: - You have been diagnosed with rheumatoid arthritis (RA) for at least 3 months. - You have been treated with at least one biological medication (a type of advanced drug for RA) for at least 3 months, but your RA is still active, or you had to stop taking it because of side effects...

**Who might be able to join this trial:** - You have been diagnosed with rheumatoid arthritis (RA) for at least 3 months. - You have been taking methotrexate (MTX) pills or injections for at least 3 months, and your dose has stayed the same for at least 4 weeks before starting the trial. - You have stopped taking all o...

**Who might be able to join this trial:** - People aged 18 to 85 years old at the time of screening - People who have been diagnosed with rheumatoid arthritis (RA) according to recognised 2010 diagnostic standards, with no signs of another condition that could be causing their lung disease - People who have been diagn...

Who might be able to join this trial: - You have been diagnosed with rheumatoid arthritis (a condition where the immune system attacks the joints) based on recognised medical guidelines. - Your rheumatoid arthritis is rated as functional class I, II, or III, meaning you have some ability to carry out daily activities (...

**Who might be able to join this trial:** - People who are 18 years of age or older. - People who have signed a consent form that has been approved by an ethics review board. - People who have been identified as a candidate for a first-time or repeat total elbow replacement surgery, due to at least one of the followin...

**Who might be able to join this trial:** *Part A – Healthy Volunteers (single dose portion of the trial):* - Adults aged 18 to 55 who are generally in good health - People who meet minimum weight requirements (at least 50 kg for men, at least 45 kg for women) and whose body weight falls within a healthy range relativ...

Who might be able to join this trial: - People who have signed the study's consent form, which has been approved by a Human Research Ethics Committee (HREC) - People diagnosed with a non-inflammatory degenerative joint condition such as osteoarthritis or avascular necrosis (bone tissue death due to reduced blood supply...

**Who might be able to join this trial:** - People who gave their informed consent before any study activities began - People who previously took part in one of the related Phase 3 Sjögren's syndrome studies (HZNP-DAZ-301 or HZNP-DAZ-303), received the study drug or placebo, and completed that study up to the Week 48...

**Who might be able to join this trial:** - You are generally healthy, as confirmed by a doctor reviewing your medical history, a physical check-up, and lab tests done during the screening process. - You are willing and able to attend all required study visits and follow the study's rules. **If you have Rheumatoid Ar...

**Who might be able to join this trial:** - You are between 18 and 75 years old (male or female) - You have been diagnosed with rheumatoid arthritis (RA) that started when you were 18 or older, and a specific blood test for RA (RF, CCP, or ACPA) has come back positive - Your RA is moderately to severely active, with a...

**Who might be able to join this trial:** - People who are able to understand the study and sign and date a consent form - People who are between 18 and 75 years old at the time of giving consent - People who have been diagnosed with Sjögren's syndrome (SS) for at least 3 months before joining the study - People who h...

**Who might be able to join this trial:** - People aged 18 to 65 years old (or the legal age of consent in the country where the trial is taking place) at the time of signing the consent form. - People diagnosed with Rheumatoid Arthritis (RA) according to recognised international classification standards (2010 EULAR/A...

Who might be able to join this trial: **Healthy participants:** - People aged 18 to 55 years old - People with a body mass index (a measure of body weight relative to height) between 18 and 32 - People who a doctor determines to be in generally good health based on a physical check-up, medical history, vital signs, an...

**Who might be able to join this trial:** - People aged 18 to 75 years old - People who have been diagnosed with rheumatoid arthritis (RA) as an adult, for at least 6 months - People whose RA is considered moderately to severely active - People whose RA has not responded well enough to previous treatment, as defined by...

Who might be able to join this trial: - Adults who are in good general health (for the healthy participant group) - Adults who have been diagnosed with idiopathic inflammatory myopathy (a condition where the immune system attacks the muscles), based on specific 2017 classification criteria used by rheumatology organis...

**Who might be able to join this trial:** - You are able to understand and sign a consent form agreeing to take part - Your overall physical health and body function are considered adequate at the start of the study - You are willing and able to stop taking certain medications for a set period of time before the study...

**Who might be able to join this trial:** - People whose body mass index (a measure of body weight relative to height) falls between 18 and 32 - People who have been diagnosed with Systemic Lupus Erythematosus (SLE) — a chronic immune system disease — for at least 6 months, and whose diagnosis meets a specific set of...

**Who might be able to join this trial:** - You must be at the legal age of consent in your country - You must have been diagnosed with active rheumatoid arthritis based on a specific set of recognized medical guidelines (the ACR 1987 Revised Criteria), with a minimum level of disease activity required to participate -...

Who might be able to join this trial: - You have been diagnosed with early rheumatoid arthritis (a condition where the immune system attacks the joints, causing pain and swelling) - You have been diagnosed with early inflammatory arthritis (joint inflammation that has been present for a short time) Who may not be able...

Who might be able to join this trial: - Adults aged 18 years or older. - People who have had rheumatoid arthritis for more than 2 years and whose rheumatologist has referred them to this study. - People with a known history of rheumatoid arthritis who are able to participate as a healthy volunteer. Who may not be able...

**Who might be able to join this trial:** - People who are able to read and sign a consent form agreeing to take part in the study - People who have been diagnosed with Sjögren's disease (a condition that affects moisture-producing glands) based on established medical classification guidelines - People who meet most of...

"Who might be able to join this trial: - People who are suspected of having sepsis, macrophage activation syndrome, Still's disease, or high ferritin levels caused by conditions such as cancer or liver cell damage. Who may not be able to join: - People whose ferritin levels are within the normal range. Important: Alw...

Who might be able to join this trial: - People older than 4 years of age who have, or are suspected of having, a disease or condition affecting the salivary glands, or who are a family member of someone with such a condition. - People aged 18 or older who have active hepatitis (with or without dry mouth or dry eye symp...

**Who might be able to join this trial:** - People who have been diagnosed with rheumatoid arthritis (RA) based on recognised international medical guidelines (EULAR/ACR 2010 criteria) - People whose RA is considered moderately to highly active, based on a standard disease activity score (DAS28-CRP above 3.2) - People...

**Who might be able to join this trial:** - People who have a severely painful or disabling hip joint caused by osteoarthritis, injury-related arthritis, a hip condition present from development (developmental dysplasia), or bone tissue death in the hip (avascular necrosis of the femoral head). - People who are between...

**Who might be able to join this trial:** - People who have been diagnosed with primary Sjögren's syndrome based on a specific set of internationally recognised diagnostic guidelines (called the American-European Consensus Criteria) - People who have been informed about the study and have signed the consent form agreei...

**Who might be able to join this trial:** - You are male or female, of any race, and your doctor has recommended a total knee replacement - You are over 22 years old and your bones have finished growing - You have a knee condition such as osteoarthritis, arthritis caused by a previous injury, inflammatory arthritis (s...

Who might be able to join this trial: - People between 19 and 90 years of age. - People who are able to give their informed consent to participate. - People who have been diagnosed with rheumatoid arthritis (RA) by a rheumatologist using a specific set of medical guidelines (the 2010 American College of Rheumatology cr...

**Who might be able to join this trial:** - You have been diagnosed with rheumatoid arthritis (RA) meeting at least 4 out of 7 specific criteria set by the American College of Rheumatology. - You had morning stiffness lasting at least 1 hour, for at least 6 weeks. - You have had swelling in 3 or more joints for at lea...

Who might be able to join this trial: - Children under 16 who meet the established medical classification criteria (called ILAR criteria) for a condition called systemic juvenile idiopathic arthritis (sJIA), which is a type of childhood arthritis with fever and inflammation - People aged 16 or older who previously met...

Who might be able to join this trial: - Children aged 2 to 17 years who have been recently diagnosed with a specific type of juvenile idiopathic arthritis (JIA) — either the type affecting a few joints (oligoarthritis) or the type affecting many joints without a certain blood marker called rheumatoid factor (RF-negativ...

Who might be able to join this trial: - People who have been diagnosed with rheumatoid arthritis. Who may not be able to join: - People who are currently pregnant or breastfeeding. - People who have liver or kidney problems. Important: Always verify eligibility with the trial site directly before applying.

Who might be able to join this trial: - You have been diagnosed with rheumatoid arthritis Who may not be able to join: - You have a liver disease or condition - You have a kidney (renal) disease or condition Important: Always verify eligibility with the trial site directly before applying.

**Who might be able to join this trial:** - You have been diagnosed with either Inflammatory Bowel Disease (IBD) or Rheumatic Disease (RD) - Your disease is currently active — for IBD, this means your bowel disease is at least mildly active (confirmed by a doctor's assessment or a stool test result above a certain lev...

**Who might be able to join this trial:** - People with documented osteoarthritis or inflammatory/degenerative changes in the knee, hip, shoulder, Achilles tendon, sacroiliac joint, wrist, hand, foot, ankle, or plantar fascia (the tissue on the bottom of the foot) - People without systemic (whole-body) disorders that...

**Who might be able to join this trial:** - People who have severe knee osteoarthritis that has reached the stage where a knee replacement is needed - People for whom a specific knee replacement system (called the ATTUNE total knee system) has been chosen as part of their normal medical care - People who are willing an...

**Who might be able to join this trial:** **For patients with a diagnosed condition:** - People aged 18 or older - People who have been diagnosed with spondyloarthritis (a type of inflammatory joint disease) or rheumatoid arthritis, based on recognised medical classification systems - People who are covered by a Frenc...

**Who might be able to join this trial:** - People who have active, disabling rheumatoid arthritis (a disease score meeting specific thresholds) even after trying a TNF-inhibitor biologic medication, or who had to stop that medication because of side effects or intolerance - People who, if taking steroid medications (...

**Who might be able to join this trial:** - People who have been diagnosed with a condition where disease activity is low or moderate (based on a scoring system called the Clinical Disease Activity Index, with a score of 22 or below) - People whose condition and treatment have been stable, with no changes in the past 3...

**Who might be able to join this trial:** - You have been diagnosed with melanoma - You have also been diagnosed with a pre-existing autoimmune condition, which must be one of the following: - **Inflammatory bowel disease** (Crohn's disease or ulcerative colitis, diagnosed by a gastroenterologist, with ulcerative co...

"Who might be able to join this trial: - You have been diagnosed with Sjögren Syndrome - You are over 18 years old - You are covered by a social security or health insurance system (not including AME) (confirm with trial site) - You can read and understand French well enough to follow the study information - You agree...

**Who might be able to join this trial:** - You were diagnosed with rheumatoid arthritis (RA) as an adult, and have had it for at least six months - You are between 22 and 75 years old (male or female) - Your rheumatoid arthritis is currently active (causing symptoms) - Your RA has not responded well enough to at least...

**Who might be able to join this trial:** - People who have been diagnosed with primary Sjögren's syndrome (pSS) based on the 2016 international classification criteria for this condition. - People who experience symptoms of dry mouth and dry eyes. - People whose blood test at the screening stage shows a positive resu...

**Who might be able to join this trial:** - You are 18 years of age or older, male or female. - You are willing and able to sign a consent form agreeing to take part in the study. - You have a good enough understanding of the Dutch language to follow the study requirements. - You have been diagnosed with rheumatoid art...

Who might be able to join this trial: - People who have been diagnosed with rheumatoid arthritis (RA) for at least six months, based on recognised 2010 diagnostic guidelines - People aged between 22 and 75 years, of any gender - People whose rheumatoid arthritis is currently active (meaning symptoms are present and ong...

Who might be able to join this trial: - You have been diagnosed with Rheumatoid Arthritis - You are willing and able to understand and sign a written consent form agreeing to take part Who may not be able to join: - You currently have an active infection - You currently have active cancer - You have long-term failure...

Who might be able to join this trial: - You must be 18 years old or older. - You must have been diagnosed with Adult Rheumatoid Arthritis based on specific 2010 medical guidelines (confirm with trial site). - You must have already received at least one dose of the medications being studied in this trial. - You must be...

**Who might be able to join this trial:** - Adults aged 18 or older - People who have been diagnosed with rheumatoid arthritis (RA) according to standard 2010 classification guidelines - People whose RA is currently active, based on a disease activity score called DAS28-CRP being 3.2 or higher - People who have not re...

**Who might be able to join this trial:** **For people with early rheumatoid arthritis (RA):** - People who are able to give written consent to participate - People aged 18 or older - People who have been diagnosed with rheumatoid arthritis according to 2010 ACR criteria, with a disease activity score (DAS28-CRP) abov...

Who might be able to join this trial: - People diagnosed with moderate to severe rheumatoid arthritis, based on a standard disease activity score (DAS-28 score above 3.2) - People aged between 18 and 60 years old whose arthritis is currently active, as confirmed by an experienced arthritis specialist - People currently...

**Who might be able to join this trial:** **Main study – Case group:** - Adults who have osteoarthritis in the hip joint and are scheduled for a planned total hip replacement surgery **Main study – Control group:** - Adults who do not have arthritis and are having an emergency total hip replacement surgery due to a t...

Who might be able to join this trial: - People who are having a total knee replacement surgery using a B. Braun knee implant system - People who have signed a written consent form agreeing to take part - People who are willing and able to use a sensor device called the "BPMpathway" - People who are willing and able to...

**Who might be able to join this trial:** - You are 18 years of age or older - You have been diagnosed with rheumatoid arthritis (RA) based on recognized medical guidelines - For one part of the study (Sub-study 1): Your standard first-line arthritis medications have not worked well enough, and your doctor considers yo...

**Who might be able to join this trial:** - People who are 18 years of age or older - People who have been diagnosed with interstitial lung disease (a condition causing scarring or inflammation in the lungs) within the last 5 years, as confirmed by a team that includes at least one lung specialist and one joint/autoim...

**Who might be able to join this trial:** - You have been diagnosed with rheumatoid arthritis (RA) - You are 18 years old or older (male or female) - You are either staying in hospital or attending an outpatient appointment in a rheumatology department, and you return home after your visit - You are currently taking or...

**Who might be able to join this trial:** - People aged 18 or older - People who have been diagnosed with rheumatoid arthritis according to the 2010 ACR-EULAR classification criteria - People who test positive for ACPA (a specific antibody associated with rheumatoid arthritis) - People who have been taking methotrexat...

**Who might be able to join this trial:** - People who are male or female, aged 18 to 55 (for the healthy volunteer part) or 18 to 70 (for the rheumatoid arthritis patient part), at the time of screening. - People with a body weight of at least 50 kg at screening. - People whose body mass index (a measure of weight re...

**Who might be able to join this trial:** - People aged between 18 and 75 years old - People who have been diagnosed with rheumatoid arthritis according to recognised international diagnostic standards (1987 ACR or 2010 ACR/EULAR criteria) - People whose rheumatoid arthritis also meets a specific Traditional Chinese M...

**Who might be able to join this trial:** - People who have been recommended for a total ankle replacement surgery - People whose bones have finished growing (skeletally mature) - People who are mentally able to complete follow-up questionnaires and forms - People who are able to attend follow-up appointments for up to...

**Who might be able to join this trial:** - You have been diagnosed with Rheumatoid Arthritis (RA) using recognised medical guidelines, AND you have problems with your knee function. - You meet the 1987 RA classification by having at least 4 of these 7 signs: morning stiffness lasting at least 1 hour (for 6+ weeks); 3...

**Who might be able to join this trial:** - Your doctor has recommended you for a total ankle replacement surgery - You are at least 21 years old - You are likely to be available for follow-up appointments for up to 10 years after surgery - You are willing to attend all required appointments before and after the proced...

Who might be able to join this trial: - People aged 18 to 74 years old with moderate to severe active rheumatoid arthritis, for whom a doctor has prescribed the medication filgotinib in line with the approved product guidelines. - People who are right-handed (this requirement helps keep brain imaging results consistent...

**Who might be able to join this trial:** - People who have been diagnosed with rheumatoid arthritis (RA) based on standard 2010 classification criteria - People aged 18 to 84 years - People whose RA is currently moderately or highly active, based on a standard disease activity score (called CDAI, scored above 10) - P...

Who might be able to join this trial: - You are 18 years old or older - You have high blood pressure that is not well controlled - You have been diagnosed with rheumatoid arthritis - You receive both your general (primary) care and your rheumatology (joint/arthritis specialist) care through the Duke Health System Who...

**Who might be able to join this trial:** - You are 18 years old or older and have been diagnosed with rheumatoid arthritis (RA) - You are currently taking a medication called methotrexate (with or without other similar RA medications) at a steady dose for at least 4 weeks, and you are either about to start a drug cal...

**Who might be able to join this trial:** - People aged 18 years or older - People who have been diagnosed with rheumatoid arthritis (RA) according to recognised international diagnostic guidelines - People who have tested positive for certain RA-related antibodies (known as ACPA and/or rheumatoid factor) found in blo...

Who might be able to join this trial: - People who are older than 18 years of age - People who have been diagnosed with one of the following shoulder conditions: primary osteoarthritis, secondary osteoarthritis, cuff tear arthropathy (a damaged or insufficient rotator cuff), an acute fracture that occurred less than 21...

**Who might be able to join this trial:** - You are a man or woman aged 18 or older - You have been diagnosed with at least one of the following conditions: Rheumatoid Arthritis, Gout, Systemic Lupus Erythematosus, or Sjögren's Syndrome (diagnosed using specific standard medical guidelines — confirm with trial site) -...

Who might be able to join this trial: - You are 18 years of age or older - You have been diagnosed with rheumatoid arthritis (RA) according to recognized medical guidelines - You have been taking the medication methotrexate for at least 12 weeks - Your rheumatoid arthritis is not well controlled, based on a specific di...

**Who might be able to join this trial:** - People aged 18 to 75 years old (inclusive). - People who are able to give written consent to participate. - Men or women (who are not breastfeeding or pregnant) who have active rheumatoid arthritis (RA), confirmed using recognised international classification criteria. - Peo...

**Who might be able to join this trial:** - People aged 20 years or older - People whose bones have finished growing and reached full maturity - People for whom a decision to have a total knee replacement using the ROSA Knee System has already been made independently, before being considered for the study - People who...

Here is the eligibility information for this clinical trial in plain language: **Who might be able to join this trial:** - People who need a total knee replacement surgery using a fixed type of knee implant - People who are willing and able to sign a written agreement to take part in the study **Who may not be able t...

**Who might be able to join this trial:** - You are willing and able to sign a consent form and take part in the study before anything begins. - You are 18 years old or older. - You can read and write in Dutch or French. - You have been diagnosed with rheumatoid arthritis based on recognised medical classification stan...

**Who might be able to join this trial:** - People who can read and speak English, so they are able to give written consent and complete questionnaires - People who are willing to sign and date a consent form agreeing to take part - People who are willing and able to follow all study procedures for the full duration o...

**Who might be able to join this trial:** - People who are scheduled to have a total knee replacement surgery on both knees, using a specific type of implant called a "posterior stabilised" (PS) type **Who may not be able to join:** - People who are unable to attend follow-up appointments, including cases of patient d...

Who might be able to join this trial: - Your Body Mass Index (BMI) must be below 35 (a measure of body weight relative to height) - You have been diagnosed with rheumatoid arthritis (RA) that started in adulthood and is considered moderate to severe - Your RA is currently moderately to severely active - You have tried...

**Who might be able to join this trial:** - People who have been diagnosed with rheumatoid arthritis (RA) according to established international classification guidelines - People who also meet recognised criteria for chronic widespread pain (long-lasting pain spread across the body) - People whose rheumatoid arthriti...

**Who might be able to join this trial:** - You are currently being prescribed Jyseleca (filgotinib) tablets in South Korea, following the approved guidelines for its use there. - You have moderate to severe rheumatoid arthritis as an adult, and previous treatments (called DMARDs) have not worked well enough for you o...

**Who might be able to join this trial:** - You have been diagnosed with rheumatoid arthritis using recognised medical guidelines (from 1987 or 2010 standards) - Your rheumatoid arthritis is currently at a moderate or high level of activity - You have had a joint tissue sample (biopsy) taken, and the results showed a...

Who might be able to join this trial: - You have been diagnosed with rheumatoid arthritis (RA) according to recognised medical guidelines - Your overall disease impact score (as rated by your doctor) is 40mm or higher on a standard scale - You are between 18 and 64 years old - You are motivated and willing to take part...

Who might be able to join this trial: - You must be an adult aged 18 or older - You must be suspected by a doctor of possibly having Sjögren's syndrome (a condition that affects the immune system and commonly causes dry eyes and dry mouth) - You must be willing to go through the full set of tests used to diagnose Sjögr...

**Who might be able to join this trial:** - You have been diagnosed with dry mouth, confirmed by a saliva flow test showing very low saliva production. - Your dry mouth is **not** caused by radiation therapy — it has a medical cause. - You are between 18 and 90 years old. - You are generally in good enough health to u...

**Who might be able to join this trial:** - Children and teenagers between 5 and 18 years old - People who have been diagnosed with Sjögren's syndrome (SS) based on recognised medical diagnostic guidelines - People whose Sjögren's syndrome has not responded well enough to treatment, meaning they have been on two or mo...

**Who might be able to join this trial:** - Doctors expect you to live for at least 3 more months. - You have a recurring or treatment-resistant autoimmune disease (such as lupus, rheumatoid arthritis, Sjögren's syndrome, or similar conditions) that has not responded to standard treatments or has no effective treatmen...

Who might be able to join this trial: - People who are 18 years of age or older - People who have been diagnosed with Rheumatoid Arthritis based on the 2010 ACR (American College of Rheumatology) criteria - People who understand what the study involves and are willing to sign a written agreement to take part Who may n...

Who might be able to join this trial: - Adults aged 18 or older, of any gender, who are able to sign a consent form in person (or have a guardian sign on their behalf) before any screening begins. - People diagnosed with rheumatoid arthritis (RA) according to recognised 2010 diagnostic guidelines, whose condition has n...

**Who might be able to join this trial:** - People who have been diagnosed with Rheumatoid Arthritis (RA) according to specific medical guidelines, and whose disease is currently considered active based on standard scoring measurements - People who are older than 18 and younger than 65 years of age - People for whom a...

**Who might be able to join this trial:** - People who have been diagnosed with rheumatoid arthritis according to a recognised set of medical guidelines (the 2010 ACR/EULAR criteria) - People who are experiencing poor sleep quality, based on a sleep questionnaire score above 7 (called the PSQI) - People whose rheumatoi...

Who might be able to join this trial: - People who are over 18 years of age - People who have been diagnosed with rheumatoid arthritis (RA) based on recognised international diagnostic guidelines (ACR/EULAR 2010 criteria) - People whose rheumatoid arthritis has been in remission (very low disease activity) for at least...

Who might be able to join this trial: - (Nomogram group) You do not have any dry mouth or dry eye symptoms. - (Sicca group) You are already receiving a salivary gland scan (a test called sialoscintigraphy) as part of your care. Who may not be able to join: - You are currently pregnant. - You are currently breastfeedin...

Who might be able to join this trial: - People who experience burning, itching, or a sensation of something in their eye - People who have been assessed as having moderate or severe dry eye - People aged between 18 and 70 years Who may not be able to join: - People who have had eye surgery in the past - People who hav...

**Who might be able to join this trial:** - You are 18 years of age or older - You are planning to have a joint replacement surgery in one of the knuckle joints of your finger using a specific implant called KeriFlex® - You have been diagnosed with rheumatoid arthritis, osteoarthritis, or arthritis caused by a previous...

Who might be able to join this trial: - People diagnosed with rheumatoid arthritis (RA) for at least 3 months before the screening visit, based on recognised international classification guidelines - People aged between 18 and 85 years old - People whose RA is currently active, shown by a specific disease activity scor...

Who might be able to join this trial: - People aged 18 to 75 who have been diagnosed with rheumatoid arthritis (RA) for at least 12 months, based on recognised international diagnostic standards - People who do not currently have any shoulder pain Who may not be able to join: - People with a suspected shoulder problem...

Who might be able to join this trial: - People who have been diagnosed with rheumatoid arthritis according to the standard 2010 classification guidelines used by doctors - People who are older than 19 years of age - People who are currently taking the medication methotrexate - People who agree to receive the Shingrix v...

Who might be able to join this trial: - People who are patients at the Waterloo Rheumatology Community Clinic - People aged between 18 and 80 years old - People who have been diagnosed with rheumatoid arthritis - People who have at least a basic working ability to read and communicate in English - People who do not hav...

**Who might be able to join this trial:** - People who were diagnosed with rheumatoid arthritis (RA) at least 6 months ago but no more than 15 years ago, based on recognised medical criteria. - People who still have moderate to severe RA symptoms despite taking methotrexate (MTX), meaning they have 6 or more swollen j...

**Who might be able to join this trial:** - Adults aged 18 or older - People who have received at least 3 doses of an mRNA COVID-19 vaccine as their primary vaccine series - People who have had a solid organ transplant (such as a kidney, liver, or heart) at least 3 months ago and are currently on standard anti-rejectio...

**Who might be able to join this trial:** - You are willing to take part, can follow all the study steps, and have signed a consent form agreeing to participate. - You have been diagnosed with Rheumatoid Arthritis (RA) for at least 3 months, your RA is moderately to severely active, and previous treatments (such as di...

Who might be able to join this trial: - The hip replacement surgery being performed must follow the approved uses for all devices involved. - The person is having their first-ever uncemented hip replacement using specific implant components (EMPHASYS cup with a CORAIL, EMPHASYS, or ACTIS stem), performed through one of...

Who might be able to join this trial: - Adults between 18 and 65 years of age. - People who have been diagnosed with established rheumatoid arthritis. - People whose rheumatoid arthritis is considered moderately to highly active, based on a specific scoring system that uses a blood marker called C-reactive protein (a s...

Who might be able to join this trial: - Adults aged 18 or older who are able to understand and sign a consent form, and who can read and communicate well enough in the local language to follow the study steps - People who have been diagnosed with rheumatoid arthritis (RA) based on established international classificati...

Who might be able to join this trial: - People who have signed and dated a consent form before any trial procedures begin. - People who have been officially diagnosed with rheumatoid arthritis (RA) according to recognised international classification standards. - People whose RA diagnosis was made no more than 6 months...

**Who might be able to join this trial:** - Adults aged 18 or older who work full-time (at least 30 hours per week) - People experiencing shoulder problems related to their work, with symptoms severe enough to score at least 14 points on a standard shoulder disability questionnaire called the QuickDASH - People whose...

**Who might be able to join this trial:** - You have been diagnosed by your doctor with moderate to severe rheumatoid arthritis (RA) that is currently active, or you have had this diagnosis in the past. - Your doctor has already independently decided to prescribe you either Upadacitinib or a TNF inhibitor (a type of bi...

**Who might be able to join this trial:** - You have been diagnosed with one of the following conditions: systemic sclerosis (scleroderma), rheumatoid arthritis, inflammatory muscle disease (including antisynthetase syndrome), mixed connective tissue disease, or Sjögren's disease, confirmed by standard medical criteria...

**Who might be able to join this trial:** - You are between 18 and 60 years old - You have been diagnosed with rheumatoid arthritis (a condition where the immune system attacks the joints) for at least 6 months, based on recognized medical guidelines - You have been taking one or more standard arthritis medications (ca...

**Who might be able to join this trial:** - You have been diagnosed with rheumatoid arthritis (RA) based on recognised medical guidelines - You are over 18 years old - You have had rheumatoid arthritis for more than 1 year - Your rheumatoid arthritis is currently active, meaning it is not well controlled (confirm with...

Who might be able to join this trial: **Rheumatoid Arthritis Group:** - People who have been diagnosed with rheumatoid arthritis - People between 18 and 65 years of age - People who are willing to voluntarily take part in the study **Control Group (people without rheumatoid arthritis):** - People between 18 and 65 ye...

**Who might be able to join this trial:** *For people with Dry Eye Syndrome:* - People aged between 20 and 75 years - People whose Schirmer's test result (a test that measures tear production) shows less than 10 mm in 5 minutes, indicating low tear production *For people with Sjögren's Syndrome (an immune system cond...

Who might be able to join this trial: - People who are older than 18 years of age - People who have been diagnosed with a chronic rheumatic disease, specifically rheumatoid arthritis, spondyloarthritis, or osteoarthritis - People who are able to complete questionnaires Who may not be able to join: - People who are und...

**Who might be able to join this trial:** - People who are over 18 years of age at the time of signing the consent form - People with active rheumatoid arthritis, measured by a disease activity score above 3.2, with at least 4 tender and 4 swollen joints (out of 28 joints assessed) - People whose rheumatoid arthritis d...

**Who might be able to join this trial:** **For the Dry Eye Syndrome group:** - People aged between 20 and 75 years - People whose Schirmer's test result (a test that measures how much moisture the eye produces) shows less than 10 mm of fluid in 5 minutes, indicating low tear production **For the Sjögren's Syndrome g...

**Who might be able to join this trial:** - People who have been diagnosed with Sjögren's disease (a condition that affects moisture-producing glands) according to internationally recognised classification standards - People who are 18 years of age or older - People who have experienced persistent dry mouth for at leas...

**Who might be able to join this trial:** - You have been diagnosed with rheumatoid arthritis (RA) within the last 6 months and are not currently taking biologic (advanced injection or infusion) RA medications, though you may be taking one or more standard RA pills such as hydroxychloroquine, methotrexate, sulfasalazi...

Who might be able to join this trial: - People who are able to understand and are willing to sign a consent form agreeing to take part - People of any gender are eligible - People aged 18 to 75 years old - People whose life expectancy is greater than 6 months - People who have been diagnosed with rheumatoid arthritis (...

Who might be able to join this trial: - You are 18 years of age or older - You have been diagnosed by a doctor with arthritis, rheumatoid arthritis, gout, lupus, or fibromyalgia - You are able to read and write in English Who may not be able to join: - You have a medical reason why you should not exercise (other than...

Who might be able to join this trial: - People who completed the earlier related study (called TLL-018-301) within the past 3 months - People aged 18 to 75 years old at the time of giving consent - Women who could become pregnant must have a negative pregnancy test before joining and must not currently be pregnant or b...

**Who might be able to join this trial:** - People who are not currently taking a biologic or targeted disease-modifying arthritis drug (called a b/tsDMARD), and who have stopped any such drug at least 4 weeks before the study starts (or at least 6 months before, for drugs that deplete B cells, such as rituximab). - P...

**Who might be able to join this trial:** - You are 18 years of age or older - You have been diagnosed with rheumatoid arthritis (RA) based on recognised medical classification guidelines - Your rheumatoid arthritis disease activity is at a moderate level or below, based on a standard scoring system called DAS28 (confi...

**Who might be able to join this trial:** - People who have never previously been treated with methotrexate (MTX), by any method of taking it - People who are 18 years of age or older at the time of signing the consent form - People who have been diagnosed with rheumatoid arthritis according to the 2010 EULAR/ACR clas...

**Who might be able to join this trial:** - People who are female - People who have been diagnosed with rheumatoid arthritis (RA) according to standard 2010 classification guidelines - People who have had rheumatoid arthritis for 2 years or less (considered "early" RA) - People currently being treated with certain stan...

**Who might be able to join this trial:** **For people with Lupus (SLE):** - People aged 18 to 70 years old at the time of signing the consent form. - People who have been diagnosed with lupus (SLE) according to recognised international classification guidelines. - People who test positive for certain lupus-related an...

Who might be able to join this trial: - People who are 18 years of age or older - People who have been diagnosed with rheumatoid arthritis based on the 2010 ACR/EULAR classification criteria - People who are currently receiving standard-dose rituximab and whose rheumatologist considers them to be responding well to it,...

**Who might be able to join this trial:** - People aged 18 to 75 years old at the time of signing the consent form - People who have been diagnosed with adult-onset rheumatoid arthritis (RA), based on a specific set of recognised classification guidelines from 2010 - People whose RA is considered moderately to severely...

**Who might be able to join this trial:** - People who are willing and able to give written consent to participate in the study - People aged 18 to 65 years old (inclusive) at the time of signing the consent form - People who have been diagnosed with rheumatoid arthritis (RA) for at least 3 months, using recognised in...

Who might be able to join this trial: - People who have been assessed as needing a total knee replacement surgery using a specific system called the OrthoPilot® Navigation System with an Aesculap knee prosthesis - People who are willing and able to sign a consent form agreeing to take part in the study - People who are...

Who might be able to join this trial: - People aged 18 or older who have been diagnosed with rheumatoid arthritis according to recognised international guidelines - People who currently live in Austria - People who have signed and dated a consent form agreeing to take part in the study Who may not be able to join: - P...

**Who might be able to join this trial:** - People who have been treated with at least one biologic or targeted synthetic DMARD (a type of specialist arthritis medication) for 3 months or more at some point before the screening visit, and whose rheumatoid arthritis remained active during that time — or who had to stop...

Who might be able to join this trial: - People who have been diagnosed with Rheumatoid Arthritis (RA) according to standard international classification guidelines (the 2010 ACR/EULAR criteria). - People who are 18 years of age or older. - People who are able to cooperate and respond to questions during the study. Who...

**Who might be able to join this trial:** - People who have been formally diagnosed with rheumatoid arthritis (RA) for at least 12 weeks before the screening visit, based on recognised international criteria. - People whose RA appears to be driven by a part of the immune system called B-cells, shown either by certain...

Who might be able to join this trial: - People who have active rheumatoid arthritis that is not currently in remission, confirmed by a standard joint activity score (called DAS28) above 2.6. - People who are currently being treated with conventional disease-modifying antirheumatic drugs (a standard class of medication...

**Who might be able to join this trial:** - People aged 18 or older, of any gender - People with an expected survival time of at least 3 months - People with moderate-to-severe active rheumatoid arthritis that has not responded to standard treatments, or where no effective treatment options are available - People whose...

Who might be able to join this trial: - People who have been diagnosed with rheumatoid arthritis (RA) according to a standard set of medical classification guidelines - People whose RA is at least moderately active, based on a disease activity score measured by a doctor - People aged 21 or older, of any gender - People...

**Who might be able to join this trial:** - People who have been diagnosed with rheumatoid arthritis (RA) according to a standard medical scoring system that looks at which joints are affected, certain blood test results, signs of inflammation, and how long symptoms have lasted (a score of at least 6 out of 10 is requ...

**Who might be able to join this trial:** - People aged 18 to 55 years, with at least 3 participants of each gender required per group - People with a BMI between 18 and 30, and a body weight of at least 50 kg for men or at least 45 kg for women - People with no significant health problems found during medical history...

**Who might be able to join this trial:** - Adults between 18 and 65 years old (inclusive) at the screening stage, of any gender, who weigh at least 35 kg. - People who have been diagnosed with rheumatoid arthritis according to recognised 2010 classification standards. - People whose rheumatoid arthritis is currently...

**Who might be able to join this trial:** - You must be willing and able to sign a consent form before taking part in the study - You must be between 18 and 75 years old at the time of your initial screening appointment - *(For Rheumatoid Arthritis patients)* You have been diagnosed with rheumatoid arthritis, your con...

Who might be able to join this trial: - People aged between 18 and 80 years old - People who have been diagnosed with primary Sjögren's syndrome (a condition that affects the immune system, often causing dry eyes and dry mouth) according to recognised 2016 classification guidelines, OR people who have been diagnosed wi...

**Who might be able to join this trial:** - Adults aged 18 years or older. - People who have been formally diagnosed with rheumatoid arthritis (RA) using a recognised set of international medical guidelines (ACR/EULAR 2010 criteria). - People whose RA is currently rated as moderate to high in activity, based on a spec...

Who might be able to join this trial: - People who are 18 years of age or older - People who have been diagnosed with rheumatoid arthritis according to a recognised set of medical classification standards (the 2010 ACR-EULAR criteria — confirm with trial site if unsure whether this applies) - People who agree not to ta...

Who might be able to join this trial: - People who have previously received at least one dose of a Sonoma Biotherapeutics gene-modified Treg therapy as part of an earlier related treatment study. - People who understand what the study involves and its risks, and are willing to sign a written consent form. - People who...

Who might be able to join this trial: - You have been diagnosed with rheumatoid arthritis (RA) according to recognised medical guidelines (either from 1987 or 2010 standards) - You are older than 18 years of age - You have been taking standard disease-modifying medications (DMARDs) for at least 1 year - Your rheumatoid...

**Who might be able to join this trial:** - People who have moderate to severe active rheumatoid arthritis (RA), with at least 6 swollen joints and at least 6 tender joints measured at two separate check-in appointments. - People who have had a formal diagnosis of RA for at least 3 months, and whose diagnosis meets th...

**Who might be able to join this trial:** - You are between 18 and 75 years old - You have been diagnosed with rheumatoid arthritis according to the 2010 American College of Rheumatology/European Union for Rheumatology classification criteria - You have a high level of disease activity, measured by a clinical scoring s...

**Who might be able to join this trial:** - People aged 18 or older - People with active moderate to severe rheumatoid arthritis that has tested positive for certain antibodies (seropositive RA) - People who have at least 6 tender and/or swollen joints out of 28 joints checked during the screening process (a joint tha...

Who might be able to join this trial: - You must have been diagnosed with Rheumatoid Arthritis (RA) that started after you turned 18 years old. - You must meet a specific set of recognized medical guidelines used to confirm a diagnosis of Rheumatoid Arthritis (confirm with trial site). - You must have at least one visi...

Who might be able to join this trial: - People who are generally healthy men or women between 18 and 45 years old (inclusive). - Men who weigh at least 50 kg and women who weigh at least 45 kg, with a body mass index (BMI) between 19.0 and 26.0 (a measure of weight relative to height). - People who are able to communic...

Who might be able to join this trial: - Adults aged 18 or older (male or female) - People who have been diagnosed with Rheumatoid Arthritis by a specialist doctor (rheumatologist) and are currently taking medication to manage the disease (either a standard or biological type of disease-modifying drug) - People who have...

Who might be able to join this trial: - Adults who have been diagnosed with rheumatoid arthritis (RA) that is moderately to severely active - People who received a confirmed RA diagnosis at least 3 months before the screening visit, meeting recognised classification standards for RA - People whose current RA treatments...

Who might be able to join this trial: - People who have been diagnosed with rheumatoid arthritis, confirmed by a rheumatologist. - People who are taking anti-inflammatory medications (such as ibuprofen or naproxen) at a steady, unchanged dose for at least 2 weeks before joining the trial. - People who have been taking...

Who might be able to join this trial: - People with a body mass index (BMI) between 18.0 and 32.0 (a measure of body weight relative to height), inclusive — this applies to certain parts of the trial only - People taking part in Parts C and D of the trial must weigh at least 50 kilograms and have a BMI between 18.0 and...

**Who might be able to join this trial:** - People aged between 18 and 65 years - People who have been diagnosed with rheumatoid arthritis based on the ACR/EULAR 2010 criteria - People whose treatment plan has not changed significantly (such as starting or adjusting disease-modifying or biologic medications, or a large...

Who might be able to join this trial: - Adults aged 18 or older - People with a rheumatoid arthritis disease activity score (DAS28) of 3.2 or below, with no swollen joints at the time of joining - People who have been diagnosed with rheumatoid arthritis for at least one year - People whose medication for rheumatoid art...

**Who might be able to join this trial:** - People who are able to understand the study and are willing to sign a written consent form - People who are enrolled in a related companion study (protocol 15-D-0051) about diseases involving the salivary glands - People who are willing to follow all study procedures and are...

**Who might be able to join this trial:** - People who are at least 18 years old - People who have been diagnosed with rheumatoid arthritis (RA) according to established 2010 classification guidelines - People whose RA is at least moderately active, meaning they have 4 or more tender joints, 4 or more swollen joints,...

**Who might be able to join this trial:** - People who are able to give written consent to participate - People who are 18 years of age or older - People who have been clinically diagnosed with rheumatoid arthritis (RA) for more than 6 months - People who have been on a stable RA treatment plan for at least 3 months an...

Who might be able to join this trial: - People who have been diagnosed with rheumatoid arthritis by a rheumatology specialist - People between the ages of 40 and 79 - People who have at least one heart disease risk factor, such as prediabetes, high blood pressure, a body mass index (BMI) over 30, or a current or past h...

**Who might be able to join this trial:** - You have been diagnosed with rheumatoid arthritis (a condition where the immune system attacks the joints) based on recognised medical guidelines - You have had this diagnosis for more than 2 years - Your rheumatoid arthritis is moderately active, based on a specific disease...

Who might be able to join this trial: - You have been diagnosed with rheumatoid arthritis based on recognised medical guidelines (the 2010 ACR/EULAR criteria) - Your rheumatoid arthritis is currently at a low level of activity, based on a specific scoring system called DAS28 (confirm with trial site) - You have pain or...

**Who might be able to join this trial:** - You are between 18 and 70 years old (any gender) - You have been diagnosed with rheumatoid arthritis (RA) for at least 24 weeks, based on recognized medical guidelines - You have tried at least one standard RA medication (called a csDMARD) in the past, and then also tried at...

**Who might be able to join this trial:** - People aged 18 to 70 years old at the time of signing the consent form. - People diagnosed with systemic lupus erythematosus (SLE) or rheumatoid arthritis (RA) — for the first part of the trial. - People diagnosed with SLE, RA, idiopathic inflammatory myopathies (a type of m...

Who might be able to join this trial: - People who are older than 18 years of age. - People with a diagnosis of rheumatoid arthritis, confirmed using the 2010 international classification criteria for this condition. - People whose rheumatoid arthritis is currently in remission or showing low disease activity, as measu...

Who might be able to join this trial: - People who have been diagnosed with rheumatoid arthritis based on the officially recognised international classification criteria (revised ACR/EULAR criteria) - People of Pakistani origin - People between the ages of 20 and 75 years old - People who have recently been started on...

Who might be able to join this trial: - People who have been diagnosed with Rheumatoid Arthritis according to the 2010 international classification standards set by the American College of Rheumatology and the European League Against Rheumatism. - People who are over 18 years old, mentally alert, and able to cooperate...

Who might be able to join this trial: - You are between 18 and 75 years old (inclusive) - You have been diagnosed with primary Sjögren's Syndrome according to recognised international guidelines (from 2016) - Your Sjögren's Syndrome is considered active enough to meet a minimum disease activity score of 5 on a specific...

Who might be able to join this trial: - People aged 18 to 70 years old at the time of signing the consent form, of any gender - People who have been diagnosed with rheumatoid arthritis (RA) according to recognised medical classification systems - People whose RA disease activity score (a measure of joint inflammation a...

**Who might be able to join this trial:** - People who have given written agreement to take part and are willing to follow the study requirements. - People aged 18 to 75 years old at the time of signing the consent form. - People with a body weight of at least 50 kg and a body mass index (a measure of body weight rela...

**Who might be able to join this trial:** - People who are willing to give their written agreement to take part, understand what the study involves, and commit to following the study procedures throughout. - People aged 18 to 70 years (inclusive) at the time of signing the consent form. - People who have been diagnose...

**Who might be able to join this trial:** - People who are able to give written agreement to take part in the study - Men and women between 18 and 60 years of age (inclusive) - People who weigh at least 45 kg and have a body mass index (a measure of body weight relative to height) of 32 or below - People who have been...

Who might be able to join this trial: - People who have been diagnosed with rheumatoid arthritis based on the 2010 international classification criteria, and who are between 40 and 60 years old. Who may not be able to join: - People who have other health conditions alongside their rheumatoid arthritis, such as diabete...

Who might be able to join this trial: **For unpaid caregivers:** - You are an unpaid (informal) caregiver for an older adult who has been diagnosed with rheumatoid arthritis (a condition causing joint inflammation and pain) - You are 18 years of age or older - The person you care for is 65 years of age or older - You...

**Who might be able to join this trial:** - Adults who have been diagnosed with rheumatoid arthritis based on recognised medical classification standards - People who, after being assessed by their doctor, are about to start or are planning to start methotrexate treatment given by injection under the skin, where the e...

**Who might be able to join this trial:** - People who have been diagnosed with either Chronic Kidney Disease (CKD) or Rheumatoid Arthritis (RA), with no other risk factors linked to their condition. - People with CKD whose kidneys are functioning at a specific reduced level (stages III or IV of the disease) and who a...

**Who might be able to join this trial:** - You must be 18 years old or older when you sign the consent form - Your vaccinations must be up to date, and you must not be planning to have any vaccines in the 3 months after your infusion - Your blood counts, liver, and kidneys must be working well enough (as confirmed by...

**Who might be able to join this trial:** - You are between 18 and 85 years old - You have been diagnosed with rheumatoid arthritis that has not responded to treatment, based on specific 2021 guidelines - You have already tried standard rheumatoid arthritis medications that did not work, and then tried two or more biol...

**Who might be able to join this trial:** - People who have active rheumatoid arthritis that is not currently in remission, confirmed by a standard disease activity score (called DAS-28) above 2.6 - People who are currently being treated with conventional disease-modifying anti-rheumatic drugs (DMARDs), which are a sta...

Who might be able to join this trial: - People (children or adults) who were prescribed the medication canakinumab before October 2021 and took it for at least 6 months to treat a condition called FMF (Familial Mediterranean Fever) or Still's disease (which includes two forms known as SJIA and AOSD). - People for whom...

**Who might be able to join this trial:** - People who have a medically confirmed diagnosis of Inflammatory Bowel Disease (IBD) or Rheumatoid Arthritis (RA) - People who currently live in the continental United States - People who are willing and able to follow specific dietary plans as part of the study **Who may not...

**Who might be able to join this trial:** - You are between 18 and 70 years old (inclusive) - You weigh between 50 and 100 kg, and your body mass index (BMI) is between 18 and 32 (a measure of weight relative to height — confirm with trial site if unsure) - You have been officially diagnosed with Rheumatoid Arthritis (...

Who might be able to join this trial: - People who have been diagnosed with rheumatoid arthritis that is moderately to severely active, even after trying more than 2 standard arthritis medications - People who have one or more risk factors for heart disease, such as high blood pressure, diabetes, smoking, or high chole...

**Who might be able to join this trial:** - People who have been diagnosed with active rheumatoid arthritis based on recognised 2010 international classification standards - People whose joint disease activity score (measured across 28 joints) is above 2.6, indicating the condition is not well controlled - People aged...

Who might be able to join this trial: - Adults aged 18 or older - People who have been diagnosed with rheumatoid arthritis (RA) according to recognised medical classification guidelines, within 12 months of their first visit to an Early Arthritis Clinic - People who started conventional arthritis medication (known as c...

Who might be able to join this trial: - People who have finished the full treatment period of the related previous study (called the "parent study") - People who agree to follow the birth control requirements set out by the trial - People who attended their follow-up visit in the parent study and showed improvement in...

Who might be able to join this trial: - People who have been diagnosed with active rheumatoid arthritis based on recognised international classification guidelines from 2010. - People whose disease activity score across 28 joints (a standard measurement of rheumatoid arthritis severity) is above 2.6, indicating active...

Who might be able to join this trial: - People who have been diagnosed with active rheumatoid arthritis based on recognised classification standards set in 2010. - People whose disease activity score across 28 joints (a standard measurement of rheumatoid arthritis severity) is above 2.6, indicating the condition is not...

**Who might be able to join this trial:** - People who have been diagnosed with rheumatoid arthritis based on recognised international criteria (ACR/EULAR) - People aged between 19 and 65 years - People whose arthritis medications have remained unchanged for at least 3 months before joining the trial - People who are w...

**Who might be able to join this trial:** - People who have been diagnosed with rheumatoid arthritis and attend community groups or charity groups related to rheumatoid arthritis - People aged 18 years or older - People who can understand written and spoken English - People who are able to make their own decision about...

Who might be able to join this trial: - Adults aged 18 years or older - People who have been diagnosed with Rheumatoid Arthritis based on the 2010 international diagnostic criteria - People whose condition meets the medical requirements for starting a type of medication called a JAK inhibitor, based on approved guideli...

Who might be able to join this trial: - People who are 18 years of age or older - Both men and women are eligible to participate - People who have had a type of shoulder replacement surgery called Reverse Shoulder Arthroplasty or Shoulder Hemiarthroplasty, for any medically accepted reason - People whose shoulder repla...

Who might be able to join this trial: - You must be 18 years old or older. - You must have been diagnosed with rheumatoid arthritis using recognised medical guidelines (from 1987 or 2010). - Your rheumatoid arthritis must have been in remission (very low disease activity) for at least 6 months before the study starts,...

Who might be able to join this trial: - People who are 18 years old or older (or the legal age of consent in the country where the study is taking place) at the time of signing the consent form. - People who have been diagnosed with rheumatoid arthritis (RA) according to recognised international classification standard...

**Who might be able to join this trial:** - People who fully understand the trial, are willing to sign a consent form, and are able to complete all required visits and procedures - Men aged 50 or older who do not wish to have children, or women who have gone through menopause, where all participants are under 70 years...