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NCT02791191

NCT02791191
Terminated Phase 2 🇦🇺 Australian site

Who may be able to join

Who might be able to join this trial:

  • A qualified doctor has diagnosed you with mild Alzheimer's disease dementia based on recognised medical guidelines.
  • You scored between 20 and 26 (inclusive) on a standard memory and thinking test called the Mini-Mental State Examination at your screening appointment.
  • A special brain scan (called a florbetapir PET scan) showed signs of a protein buildup in the brain linked to Alzheimer's disease.

Who may not be able to join:

  • You have a significant brain or nervous system condition other than Alzheimer's, such as another type of dementia, a serious brain infection, Parkinson's disease, multiple concussions, or epilepsy or repeated seizures (childhood febrile seizures may be an exception — confirm with trial site).
  • You have an eye condition that would make it difficult to reliably test your vision or examine the back of your eye.
  • You are currently taking certain strong medications that affect how the body breaks down drugs through a liver enzyme called CYP3A (confirm with trial site which medications apply).
  • You have a known sensitivity or allergic reaction to florbetapir or a related substance called ¹⁸F-AV-1451, which are used in the brain scans.
  • You are unable to have an MRI or PET scan, or you have very difficult-to-access veins for blood tests.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.

Trial details

Status
Terminated
Phase
Phase 2
Sponsor
Eli Lilly and Company
Registry
clinicaltrials_gov
Start date
16 June 2016
Est. completion
2 July 2018

Where this trial is recruiting

🇦🇺 Australia 🇨🇦 Canada 🇯🇵 Japan 🇺🇸 United States

10 site(s) in Australia. Confirm current status and contact details directly with the trial site.

Primary endpoints

Change From Baseline in ¹⁸F-AV-1451 Positron Emission Tomography (PET) Standard Uptake Value Ratio (SUVr) at 52 Weeks

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 30 June 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

View original record on ClinicalTrials.gov