Sleep Disorders Trial, Recruiting

Written by an AI model from the ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People who are healthy men, or women who are not pregnant and not breastfeeding, between 18 and 39 years old (inclusive)
• People who are able to show they understand the study rules by scoring at least 80% on a short multiple-choice quiz (one retest is allowed if the first attempt is not passed)

Who may not be able to join:

• People who typically sleep less than 6 hours or more than 9 hours per night on average
• People whose usual bedtime on weeknights (Sunday through Thursday) is before 9:00 PM or after 11:00 PM on average
• People whose usual weekday wake-up time is after 8:00 AM on average
• People who nap more than once a week as part of their regular routine
• People whose sleep is regularly unrefreshing, based on scores from a specific sleep quality questionnaire (confirm with trial site)
• People who typically take more than 20 minutes to fall asleep on average
• People who consume more than 400 mg of caffeine per day on average (roughly 4 cups of coffee or 8 caffeinated sodas)
• People whose score on a body-clock preference questionnaire falls outside a specific range, suggesting very strong morning or evening preferences (confirm with trial site)
• People who score 14 or above on a depression questionnaire
• People who score 41 or above on an anxiety questionnaire
• People with a history of heart conditions, including irregular heartbeat, heart valve problems, heart failure, cardiac arrest, or heart attack
• People with a history of neurological conditions such as epilepsy, seizures, memory loss disorders, hydrocephalus, multiple sclerosis, narcolepsy, or other sleep disorders
• People with a lung condition that requires daily use of an inhaler
• People with kidney disease or known kidney problems
• People with liver disease or known liver problems
• People with a history of a psychiatric condition that required hospitalisation or psychiatric medication within the last 2 years, or for more than 3 months at any one time
• People who have smoked or used nicotine products more than once a week within the past year
• People who drink 14 or more alcoholic drinks per week, or whose alcohol use is considered heavy by the examining study doctor
• People who use medications or products that cannot be safely stopped during the in-laboratory parts of the study, as determined by the examining study doctor on a case-by-case basis
• People who currently use illicit drugs, including but not limited to benzodiazepines, amphetamines, cocaine, or marijuana
• People with a positive pregnancy test result
• People with a resting blood pressure above 140/90 or a resting heart rate above 110 beats per minute (a repeat measurement within range may allow continued consideration)
• People with a BMI of 30 or above
• People with blood or chemistry test results that the study doctor considers clinically significant (repeat testing may be offered)
• People with a positive urine nicotine or cotinine test at the screening visit
• People with a positive urine drug test at the screening visit
• People who have used any sleep aids within the year before screening
• People who are unable to read and sign the consent form
• People who do not have access to a quiet, dark sleep environment between 9:00 PM and 7:00 AM for a seven-night period at the start of the study
• People who are currently taking part in another clinical trial
• People whose initial screening clearance was more than 90 days before the study session start date (re-screening would be required in that case)

Important: Always verify eligibility with the trial site directly before applying.