Trial results
AI generated results summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
According to the results reported on ClinicalTrials.gov, this trial enrolled 42 people who had undergone nasal surgery — 16 in a control group and 26 in an ibuprofen group. All 42 participants completed the trial with no drop-outs. The trial was measuring post-operative pain levels, nasal bleeding, and the number of opioid (strong painkiller) pills taken each day after surgery. Pain and bleeding were measured using a visual analogue scale — essentially a 10-centimetre line where 0 means none at all and 10 means the worst imaginable. The reported data shows that for post-operative pain, the control group scored between 3.0 and 3.3 out of 10 across the different measurement time points, while the ibuprofen group scored between 1.7 and 2.3 out of 10. For nasal bleeding on the 0–10 scale, the control group recorded scores of 3.2 and 1.2 across time points, compared with 2.3 and 0.5 for the ibuprofen group. On a separate 0–4 bleeding scale, the control group scored 1.5 and 0.7, while the ibuprofen group scored 0.9 and 0.3. For opioid pill use, the reported data shows both groups took an average of 4 pills per day — the same number for each group. These are the results as reported to ClinicalTrials.gov. They are not medical advice — always discuss what they mean for you with your doctor.
View full results on ClinicalTrials.gov ↗
These are the results as reported to ClinicalTrials.gov, not medical advice. Verify independently with the trial site and discuss what they mean for you with your doctor.
Phase 3 Chronic Rhinosinusitis Trial, Completed
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- You have been diagnosed with chronic rhinosinusitis (a long-term sinus condition) and are scheduled to have sinus surgery (a procedure to improve airflow through the sinuses)
- You are over 18 years old
- You are able to speak and read English
Who may not be able to join:
- You cannot take anti-inflammatory pain medicines like ibuprofen due to a health reason, such as chronic kidney disease, stomach ulcers, or a sensitivity to aspirin that affects your breathing (confirm with trial site)
- You have a history of a bleeding disorder
- You have sinus cancer
- You have Cystic Fibrosis
- You are currently taking blood-thinning or anti-clotting medications during or immediately after the surgery
- You have a history of long-term pain conditions, fibromyalgia, or addiction to opioid (strong painkiller) medications
- You experience excessive bleeding during the surgery, as judged by your surgeon
- You are unable to take acetaminophen (paracetamol/Tylenol) for any reason
- You currently take pain relief medicines every day, including ibuprofen, other anti-inflammatory drugs, acetaminophen, strong prescription painkillers, or any other pain relievers
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Pain Visual Analogue Scale (VAS); Pain Visual Analogue Scale; Pain Visual Analogue Scale
Can't join this trial?
Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.