Printed from Voxsanity (voxsanity.com.au) — NCT03121066 — Data sourced from ClinicalTrials.gov. Verify directly with the trial site before attending. Not medical advice.
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Alzheimer's Disease Trial, Not Yet Recruiting
NCT03121066
voxsanity.com.au · Eligibility summary from public government registries · 18 August 2026 · not medical advice
Who may and may not be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who may be able to join
- A person must have been diagnosed with Alzheimer's disease using the official diagnostic guidelines set by the National Institute on Ageing and the Alzheimer's Association.
- A person must be between 60 and 75 years of age.
- A person must have scored between 20 and 26 on a standard memory and thinking test called the Mini Mental State Examination.
- A person must have scored 3 or 4 on a scale called the Global Deterioration Scale, which measures the stage of memory decline.
- A person must be able to manage basic daily tasks independently, as measured by a specific part of the Blessed Scale (Part C, scored at 0).
- A person must have scored 4 or below on the Rosen Ischemia Scale, which checks for signs related to blood vessel problems in the brain.
- A person must be able to read and write.
- A person's overall health and any medications they are taking must have been stable for at least 3 months before the study begins.
- A person must have had a CT scan and MRI brain scan within the 12 months before being considered for the trial, with results consistent with a probable Alzheimer's disease diagnosis.
- A person must have no significant abnormal findings in their medical history or laboratory test results at the time of screening.
- A person must have had a set of blood and lab tests within the 12 months before selection, all falling within normal ranges, to rule out other causes of memory problems — these tests include a full blood count, thyroid hormones, T4, folic acid, vitamin B12, albumin, several liver-related markers, sodium, potassium, urea, creatinine, and fasting blood sugar.
- A person must currently be receiving treatment with a type of medication called Acetylcholinesterase Inhibitors, which are commonly used to treat Alzheimer's disease.
- A person must have signed a consent form that has been approved by the relevant Research Ethics Committee.
Who may not be able to join
Each point below is a reason the trial team may not be able to accept someone. It is not a list of requirements to meet.
- A person who learned Spanish or Catalan after the age of 15 may not be eligible.
- A person who has had fewer than 4 years of formal schooling may not be eligible.
- A person with a low premorbid (pre-illness) intellectual ability, as measured by a vocabulary-based IQ test scoring below 85, may not be eligible.
- A person with uncontrolled medical conditions or serious mental health disorders that could affect the brain or nervous system — including signs of increased pressure in the skull or lesions inside the skull — may not be eligible.
- A person who has one or more risk factors related to blood vessel health may not be eligible.
- A person with uncontrolled medical conditions that could lead to a medical emergency involving seizures (for example, certain heart conditions, irregular heart rhythm, or asthma) may not be eligible.
- A person with a history of seizures, a prior diagnosis of epilepsy, a previously recorded abnormal brainwave test (EEG), or a family history of epilepsy may not be eligible.
- A person with severe hearing difficulties or persistent ringing in the ears (tinnitus) may not be eligible.
- A person with severe loss of vision may not be eligible.
- A person experiencing moderate or severe depression, based on a score above 11 (moderate) or 19 (severe) on the Geriatric Depression Scale, may not be eligible.
- A person who has tremors or difficulties controlling movement in the dominant arm or hand may not be eligible.
- A person currently taking certain medications listed in the trial's safety guidelines may not be eligible (confirm with trial site for the specific list).
- A person with a history of drug or alcohol misuse in the 24 months before the study may not be eligible.
- A person who has metal implants in the brain (excluding standard dental fillings) may not be eligible.
- A person who has certain medical devices, such as a pacemaker, implanted medication pump, vagal nerve stimulator, deep brain stimulator, transcutaneous electrical stimulation unit, a VP shunt, titanium plates, cochlear implants, aneurysm clips, or similar devices, may not be eligible.
- A person who has a strong negative reaction toward new technology may not be eligible.
- A person whom the lead researcher considers unsuitable for the study for any other reason may not be eligible.
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
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Trial details
Status
Not Yet Recruiting
Phase
Not Applicable
Sponsor
Universitat Oberta de Catalunya
Registry
ClinicalTrials.gov
Start date
1 November 2027
Est. completion
1 November 2027
Primary endpoints
Change in Cognitive improvement
Can't join this trial?
Data last synced from ClinicalTrials.gov: 13 August 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.
Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.