Heart Disease Trial, Recruiting NCT03197350 Sponsor: Cliniques universitaires Saint-Luc- Université Catholique de Louvain Condition: Heart Disease
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Heart Disease Trial, Recruiting

NCT03197350
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have been diagnosed with heart failure and experience typical symptoms and signs of the condition, with a functional severity rating of Class II or above (meaning symptoms appear during ordinary activity or less)
  • People whose heart failure blood marker (NT-proBNP) is above 350 pg/mL, or who have been hospitalised for heart failure in the past 12 months
  • People with a weakened pumping heart (HFrEF) where the heart pumps out less than 40% of its blood with each beat
  • People with a stiffened heart (HFpEF) where the heart pumps out 50% or more of its blood with each beat, along with specific signs that the heart is not relaxing properly (confirm specific measurements with trial site)
  • People without any history of heart failure or previous heart disease may also be eligible to join as a comparison group

Who may not be able to join:

  • People with serious heart valve disease
  • People with certain types of heart muscle disease where the muscle is abnormally thickened or infiltrated by other substances
  • People who have had an acute heart attack or serious chest pain episode within the past 30 days
  • People with severe chronic lung disease (rated as GOLD stage 3 or 4)
  • People with heart defects present from birth
  • People with disease affecting the sac surrounding the heart
  • People with severely reduced kidney function (eGFR below 15 mL/min/1.73m²) or who require dialysis
  • People with an irregular heart rhythm (atrial fibrillation) where the heart is beating faster than 140 beats per minute
  • People with severe anaemia (very low red blood cell levels, specifically haemoglobin below 8 g/dL)
  • People with significant liver problems
  • People currently dealing with active cancer

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 26 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Anne Catherine Pouleur, Cliniques universitaires Saint-Luc- Université Catholique de Louvain

Phone: 003227646600

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Registry
ClinicalTrials.gov
Start date
4 December 2014
Est. completion
1 December 2028

Where this trial is recruiting

🇧🇪 Belgium

Primary endpoints

Prognosis with a follow up including HF hospitalizations and/or deaths.

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 26 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov