Rheumatoid Arthritis Trial, Recruiting NCT03510442 Sponsor: National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) Condition: Rheumatoid Arthritis
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Rheumatoid Arthritis Trial, Recruiting

NCT03510442
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • Children under 16 who meet the established medical classification criteria (called ILAR criteria) for a condition called systemic juvenile idiopathic arthritis (sJIA), which is a type of childhood arthritis with fever and inflammation
  • People aged 16 or older who previously met the ILAR classification criteria for sJIA at some point in their life
  • People aged 16 or older who meet the established classification criteria (called Yamaguchi criteria) for a condition called adult-onset Still's disease (AOSD), a rare inflammatory condition, including having had certain blood tests come back negative
  • People aged 16 or older who were previously diagnosed with AOSD in the past, even if they no longer show active signs of the disease
  • Family members of people in the above groups
  • People with suspected sJIA, AOSD, or a similar inflammatory condition, shown by episodes of fever and/or joint pain and swelling
  • Healthy volunteers or comparison participants (both children and adults) who are willing to provide a blood sample for research comparison purposes, as long as they are not pregnant

Who may not be able to join:

  • Adults who are unable to give their own informed consent and do not have a legally authorised representative available to consent on their behalf; or children who do not have a parent or guardian available to consent
  • People whose other medical conditions could, in the opinion of the research team, make the study results difficult to interpret
  • People who are not available or are unable to attend the required follow-up visits
  • People who are pregnant
  • People who do not have known or suspected sJIA, AOSD, or a related inflammatory condition will not be followed in the study

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Michael J Ombrello, M.D., National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

Phone: (301) 827-1849

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Registry
ClinicalTrials.gov
Start date
21 May 2018
Est. completion
1 January 2050

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Genetic sequencing of patients

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov