Cardiomyopathy Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

As a healthy volunteer:

• People aged 7 years or older who do not have a known heart or cardiovascular condition
• People who are able to follow instructions and lie still inside an MRI scanner
• People who are able to give written consent, or whose parent or guardian is able to give consent on their behalf
• People who are willing to follow all study procedures and attend all scheduled appointments

As a participant with known or suspected heart disease:

• People aged 7 years or older who have a known or suspected heart or cardiovascular condition
• People who are able to give written consent, or whose parent or guardian is able to give consent on their behalf
• People who are willing to follow all study procedures (including any required food restrictions) and attend all scheduled appointments

As a participant with a non-heart-related medical condition:

• People aged 7 years or older who have a known or suspected condition affecting the brain, blood, cancer, hormones, lungs, or another non-heart-related area of the body
• People who are able to give written consent, or whose parent or guardian is able to give consent on their behalf
• People who are willing to follow all study procedures (including any required food restrictions) and attend all scheduled appointments

Who may not be able to join:

Healthy volunteers:

• People who have had a significant or long-term medical condition, particularly major heart-related conditions such as a heart attack, a heart defect present from birth, or a diagnosed disease of the heart muscle
• People whose MRI safety screening form indicates that an MRI scan may not be safe for them — this includes those with a cardiac pacemaker or implantable defibrillator (unless it is specifically labelled as MRI-safe or MRI-conditional), a brain aneurysm clip (unless MRI-safe), a nerve stimulator such as a TENS unit (unless MRI-safe), any type of ear or cochlear implant (unless MRI-safe), metal fragments in the eye, metal shrapnel or a bullet in the body (unless cleared by X-ray as MRI-safe), or any implanted device such as an insulin pump (unless labelled MRI-safe or MRI-conditional)
• People whose kidney function test results (measured within the past two weeks) fall below a certain level — these participants may still be able to take part but would not be given the MRI contrast dye
• People who are pregnant — pregnancy testing will be required in some cases before the scan; people who are post-menopausal or have had a surgical procedure that prevents pregnancy are exempt from this testing
• Children and people who are breastfeeding are not given contrast dye; breastfeeding participants may still take part if they are willing to discard breast milk for 24 hours after receiving contrast (confirm with trial site)
• Healthy volunteer children will not receive contrast dye
• Healthy volunteers who have already had two MRI scans with contrast dye (gadolinium-based) within the past year, or whose two contrast scans were less than 18 hours apart, would not be able to have further contrast scans within that period

Participants with known or suspected heart disease:

• People whose MRI safety screening form indicates that an MRI scan may not be safe for them (same implant and device criteria as listed above for healthy volunteers)
• People who are pregnant (same pregnancy testing rules as above apply; post-menopausal and surgically sterilised participants are exempt)
• People who are breastfeeding, unless they are willing to discard breast milk for 24 hours after receiving contrast dye
• People whose kidney function test results fall below a certain level (measured within the past two weeks) — these participants may still be able to take part but would not be given contrast dye
• People whose heart or breathing condition is considered unstable at the time of enrolment, as assessed by the enrolling doctor

Participants with a non-heart-related medical condition:

• People whose MRI safety screening form indicates that an MRI scan may not be safe for them (same implant and device criteria as listed above)
• People who are pregnant (same pregnancy testing rules as above apply; post-menopausal and surgically sterilised participants are exempt)
• People who are breastfeeding and receiving contrast dye, unless they are willing to discard breast milk for 24 hours afterward
• People whose kidney function test results fall below a certain level (measured within the past two weeks) — these participants may still be able to take part but would not be given contrast dye
• People whose heart or breathing condition is considered unstable at the time of enrolment, as assessed by the enrolling doctor

Important: Always verify eligibility with the trial site directly before applying.