Phase 2 Cardiomyopathy Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People who are older than 18 years of age
- People who have been diagnosed with a heart condition called ARVD (a disease affecting the right side of the heart), confirmed using specific international diagnostic guidelines that require a combination of major and minor diagnostic findings
- People whose heart is pumping at least 40% of its normal capacity (confirmed by heart scan)
- People who are willing and able to give written consent to participate
Who may not be able to join:
- People who are under legal/judicial protection
- Women who are pregnant, breastfeeding, or capable of becoming pregnant and who have not agreed to use highly effective contraception throughout the study (women are considered post-menopausal after at least 24 consecutive months without a period if aged 55 or under, or 12 months if older than 55, or if surgically sterilised)
- People who do not have health insurance
- People with severe right-sided heart failure where the right heart chamber is enlarged beyond a certain size
- People who cannot safely take a medication called spironolactone due to conditions such as kidney problems, high potassium levels in the blood, no urine output, advanced liver disease, a condition called Addison's Disease, a known allergy or sensitivity to spironolactone or its ingredients, certain sugar absorption problems, or those already taking certain other medications that interact with it (confirm with trial site)
- People who must take a specific combination of certain blood pressure medications together (confirm with trial site)
- People currently experiencing an active phase of a serious body-wide illness
- People with an underactive thyroid that is not yet treated or controlled
- People with an acute (sudden/active) overactive thyroid
- People whose right heart chamber volume is measured as normal (confirm with trial site)
- People who have had a heart transplant
- People who have difficulty swallowing
- People already participating in another clinical trial that could affect this study's results
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Philippe Chevalier, MD, PhD, Hospices Civils de Lyon
Phone: 426739447
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Right ventricle longitudinal strain measured by echocardiography; Right ventricle infundibulum diameter measured by echocardiography; number of ventricular extrasystoles > 500 on 24h-Holter ECG
Can't join this trial?
Data last synced from ClinicalTrials.gov: 21 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.