Phase 3 Gastroparesis Trial, Terminated NCT03786380 Sponsor: Allergan Condition: Gastroparesis
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Trial results

AI generated results summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

According to the results reported on ClinicalTrials.gov, this trial involved 202 participants in total, spread across five different treatment groups. The groups varied in whether participants received the study drug relamorelin, a placebo (an inactive substance), or a combination of both across different stages of the trial. The trial was primarily measuring how many participants experienced notable medical events, unusual laboratory test results, changes in vital signs (such as blood pressure and heart rate), or unusual heart-tracing (ECG) results while on the study drug. The reported data shows that when it came to unwanted medical events that appeared or worsened during treatment — known as "treatment-emergent adverse events" — the numbers ranged across the five groups: 16, 11, 27, 27, and 16 participants respectively reported at least one such event. For laboratory test results that were flagged as potentially clinically significant (meaning they stood out enough for the investigator to take note), the reported data shows very small numbers — mostly zero participants per group, with a handful of isolated individual results noted in certain groups. For vital signs, the reported data shows that no participants in any group were recorded as having clinically meaningful trends. Similarly, for heart-tracing (ECG) results, no participants in any group were recorded as having clinically meaningful trends. It is worth noting that the data shows zero participants recorded as having "completed" the trial in the conventional sense, which may reflect how the study's completion was defined and recorded rather than participants dropping out. These summary numbers are what was submitted to the registry and do not include further context about the nature of individual events. These are the results as reported to ClinicalTrials.gov. They are not medical advice — always discuss what they mean for you with your doctor.

These are the results as reported to ClinicalTrials.gov, not medical advice. Verify independently with the trial site and discuss what they mean for you with your doctor.

Phase 3 Gastroparesis Trial, Terminated

NCT03786380
Terminated Phase 3 🇦🇺 Australian site

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You must have already successfully completed one of two specific earlier related studies (called RLM-MD-03 or RLM-MD-04)
  • You must be able to read and sign a consent form agreeing to take part before any study activities begin, and be willing and able to follow the study's requirements
  • You must have followed the rules and procedures of the earlier study well enough, as judged by the study doctor

Who may not be able to join:

  • You are planning to take part in another study involving an experimental drug or medical device at any point during this trial
  • You have an ongoing health concern or abnormal test result (such as a physical exam finding, blood test, or heart tracing) left over from the earlier study that the study doctor feels could affect your ability to take part safely
  • You have any other condition or situation that the study doctor believes could affect the study results or put you at risk, including serious kidney, liver, or heart and lung problems
  • You are currently pregnant, breastfeeding, or planning to become pregnant during the study

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
Phase 3: approximately ~65% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Harvy Schneier, Allergan

Australian sites

Nepean Hospital, Kingswood, New South Wales
Princess Alexandra Hospital, Woolloongabba, Queensland
Royal Adelaide Hospital - Central Adelaide Local Health Network Incorporated, Adelaide, South Australia
The Alfred Hospital, Melbourne, Victoria
Royal Melbourne Hospital, Parkville, Victoria

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Terminated
Phase
Phase 3
Sponsor
Registry
ClinicalTrials.gov
Start date
20 December 2018
Est. completion
5 October 2020

Where this trial is recruiting

🇦🇷 Argentina 🇦🇺 Australia 🇦🇹 Austria 🇧🇪 Belgium 🇧🇷 Brazil 🇧🇬 Bulgaria 🇨🇦 Canada 🇨🇴 Colombia 🇩🇰 Denmark 🇫🇷 France 🇩🇪 Germany 🇭🇺 Hungary 🇮🇳 India 🇮🇱 Israel 🇮🇹 Italy 🇱🇻 Latvia 🇲🇾 Malaysia 🇲🇽 Mexico 🇵🇭 Philippines 🇵🇱 Poland 🇷🇴 Romania 🇷🇺 Russia 🇸🇬 Singapore 🇿🇦 South Africa 🇰🇷 South Korea 🇪🇸 Spain 🇹🇭 Thailand 🇺🇦 Ukraine 🇬🇧 United Kingdom 🇺🇸 United States

5 site(s) in Australia. Confirm current status and contact details directly with the trial site.

Primary endpoints

Number of Participants Who Experienced One or More Treatment-Emergent Adverse Events (TEAEs); Number of Participants With Potential Clinically Significant (PCS) Clinical Laboratory Results; Number of Participants With Clinically Meaningful Trends for Vital Signs; Number of Participants With Clinically Meaningful Trends in Electrocardiogram (ECG) Results

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov