Phase 2 Sleep Disorders Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People who experience more than 10 breathing interruptions per hour during non-REM (lighter stage) sleep while lying on their back, as measured by a sleep study.

Who may not be able to join:

• People who have a medical condition other than well-controlled high blood pressure or mild diabetes.
• People who take any medication known to affect breathing, sleep, wakefulness, or muscle function.
• People who have a fear of enclosed spaces (claustrophobia).
• People who are unable to sleep on their back.
• People who have an allergy to any of the medications being tested in this trial.
• People who have a history of kidney stones, high calcium levels in the blood, overactive parathyroid glands, sarcoidosis, or too much vitamin D in the body.
• People who have an underlying heart condition, such as an irregular heartbeat.
• People who take psychiatric medications, including MAO inhibitors, SSRIs, SNRIs, or any of the specific medications being studied in this trial for an existing medical condition.
• Women who are pregnant.
• People who have high blood pressure in the lungs (pulmonary hypertension).
• People with severe sleep apnoea where the average blood oxygen level drops below 88% during sleep.

Important: Always verify eligibility with the trial site directly before applying.