Heart Disease Trial, Recruiting NCT03858777 Sponsor: Nabeel Hamzeh Condition: Heart Disease
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Heart Disease Trial, Recruiting

NCT03858777
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

This trial has four different groups. You may qualify for one of them:

Group 1 – Sarcoidosis patients without heart inflammation:

  • You have been diagnosed with sarcoidosis according to recognised medical guidelines (ATS/ERS criteria) (confirm with trial site)
  • You have had a normal 12-lead ECG (heart tracing test) within the past year
  • You are a non-smoker
  • You have not taken any immune-suppressing medications for at least one year

Group 2 – Sarcoidosis patients with signs of active heart inflammation:

  • You have been diagnosed with sarcoidosis according to recognised medical guidelines (ATS/ERS criteria) (confirm with trial site)
  • A recent heart MRI or PET scan has shown signs of active inflammation in your heart
  • You are a non-smoker

Group 3 – People who have recently had a heart attack (STEMI):

  • Your heart attack was confirmed by a specific pattern on a heart tracing test (ECG)
  • Your symptoms started within the last 12 hours
  • You are currently receiving a heart procedure to treat an acute blockage
  • You are able to give consent for a blood draw

Group 4 – Healthy volunteers:

  • You have no known heart disease
  • You do not have high blood pressure or diabetes
  • You are a non-smoker

Who may not be able to join:

Group 1:

  • You have a known heart condition
  • You currently smoke
  • You are currently taking immune-suppressing medications

Group 2:

  • You have a known heart condition other than sarcoidosis
  • You currently smoke
  • You are currently taking immune-suppressing medications

Group 3:

  • You currently smoke
  • Your condition is medically unstable at the time of the study (confirm with trial site)

Group 4:

  • No specific exclusion criteria listed beyond not meeting the inclusion requirements above (confirm with trial site)

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 5 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Nabeel Hamzeh, MD, University of Iowa

Phone: 319-353-8862

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Nabeel Hamzeh
Registry
ClinicalTrials.gov
Start date
1 May 2019
Est. completion
15 December 2027

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

cfDNA level

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 5 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov