Hearing Loss Trial, Recruiting NCT03914378 Sponsor: University of Manchester Condition: Hearing Loss
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Hearing Loss Trial, Recruiting

NCT03914378
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

Prospective Patient Group (joining before treatment):

  • People who have been diagnosed with head and neck cancer
  • People whose medical team has decided their treatment will involve radiotherapy, with or without a chemotherapy drug called cisplatin

Retrospective Patient Group (joining after treatment):

  • People who were previously diagnosed and treated for head and neck cancer
  • People who received radiotherapy directed to one side of the head
  • People who are within 5 years of finishing their treatment
  • People whose medical team decided on treatment involving radiotherapy, with or without cisplatin chemotherapy

Retrospective Normal-Hearing Control Group:

  • People whose hearing test results show no significant hearing loss (confirm with trial site)

Retrospective Hearing-Impaired Control Group:

  • People whose hearing test results show a certain level of hearing loss (confirm with trial site)

Who may not be able to join:

Prospective Patient Group:

  • People who had a hearing loss above a certain level before the study, based on a hearing test (confirm with trial site)
  • People who already use or need a hearing aid
  • People whose medical team decided on a chemotherapy drug called carboplatin instead of cisplatin
  • People already taking part in another research study where the treatment is known to cause hearing damage
  • People who are not able to give their own informed consent to participate

Retrospective Patient Group:

  • People whose medical team decided on carboplatin-based chemotherapy
  • People who are not able to give their own informed consent to participate

Retrospective Normal-Hearing Control Group:

  • People whose hearing test shows any hearing loss above a certain level at specific frequencies (confirm with trial site)
  • People who are not able to give their own informed consent to participate

Retrospective Hearing-Impaired Control Group:

  • People who are not able to give their own informed consent to participate

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 26 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Phone: +44(161)275 3394

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
University of Manchester
Registry
ClinicalTrials.gov
Start date
1 May 2019
Est. completion
1 December 2026

Where this trial is recruiting

🇬🇧 United Kingdom

Primary endpoints

Change in Audiology test results for prospective cohort; Audiology test results for retrospective cohort

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 26 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov