Phase 2 Rheumatoid Arthritis Trial, Recruiting NCT03938701 Sponsor: University Medical Center Groningen Condition: Rheumatoid Arthritis
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Phase 2 Rheumatoid Arthritis Trial, Recruiting

NCT03938701
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You have been diagnosed with either Inflammatory Bowel Disease (IBD) or Rheumatic Disease (RD)
  • Your disease is currently active — for IBD, this means your bowel disease is at least mildly active (confirmed by a doctor's assessment or a stool test result above a certain level); for Rheumatic Disease, this means at least one joint in your hand is currently inflamed, as confirmed by a specialist
  • You are 18 years old or older and are able to make your own decisions
  • You are willing and able to sign a written consent form
  • If you have IBD, you must already have a colonoscopy (camera test of the bowel) booked for medical reasons
  • If you are a woman who could become pregnant, you must have a negative pregnancy test before joining, and be willing to use effective contraception during the study and for 3 months afterwards

Who may not be able to join:

  • People whose physical or mental health conditions prevent them from fully understanding and agreeing to take part
  • Women who are currently pregnant or breastfeeding
  • Patients with Rheumatic Disease who have a darker skin tone above a certain level on a medical skin colour scale (called the Fitzpatrick scale, type 3 or above), due to limitations of the measurement equipment used in the study (confirm with trial site)

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 7 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Wouter B. Nagengast, MD, PhD, PharmD, University Medical Center Groningen

Phone: +31503612620

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Registry
ClinicalTrials.gov
Start date
6 August 2024
Est. completion
1 March 2026

Where this trial is recruiting

🇳🇱 Netherlands

Primary endpoints

Safety: number of participants with symptoms or changes in vital signs (blood pressure, heart rate and temperature) that are related to administration of adalimumab-800CW; Safety: number of participants with (serious) adverse events that are related to the administration of adalimumab-800CW; Discrimination of inflamed and normal tissue based on in vivo fluorescence measurements from adalimumab-800CW gained during fluorescence imaging of the hand of rheumatoid arthritis patients; Discrimination of inflamed and normal tissue based on in vivo and ex vivo fluorescence measurements from adalimumab-...

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 7 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov