Phase 2 Breast Cancer Trial, Not Yet Recruiting
voxsanity.com.au · Eligibility summary from public government registries · 18 August 2026 · not medical advice
Who may and may not be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who may be able to join
- Women between 18 and 70 years old
- People who have completed surgery to fully remove the tumour (radical surgery)
- People whose breast cancer has been confirmed by laboratory testing as a specific type called invasive ductal carcinoma
- People whose tumour was smaller than 8mm, had not spread to the lymph nodes, and showed no signs of spreading elsewhere in the body
- People whose removed tumour tissue has been tested and found to be HER2-positive (a specific protein marker on cancer cells) at a high level, with a nuclear grade of 3 (confirm with trial site for exact testing details)
- People who have enough tumour tissue available for multiple tissue samples to be taken
- People for whom fewer than 84 days have passed since their surgery, and whose surgical wound has healed adequately as assessed by their treating doctor
- People who are in good general health, able to carry out daily activities with little or no limitation (ECOG score 0–1), and expected to live longer than 12 months
- People whose heart is functioning normally, with a heart pumping strength (LVEF) of 50% or above, confirmed by a heart scan or ultrasound
- People with adequate bone marrow, liver, kidney, and blood clotting function
- Women who could become pregnant must have a negative pregnancy test within 7 days of starting the study drug, and must agree to use an effective form of contraception throughout the study
- People who have given written informed consent in line with local ethics committee requirements
Who may not be able to join
Each point below is a reason the trial team may not be able to accept someone. It is not a list of requirements to meet.
- People whose tumour was 8mm or larger, or whose cancer had spread to the lymph nodes
- People whose breast cancer has spread to other parts of the body (metastatic breast cancer)
- People who have previously received any systemic or localised treatment for breast cancer, including chemotherapy within the past 28 days
- People with a history of another cancer, except for certain early-stage cervical cancer or a type of non-spreading skin cancer (basal cell carcinoma)
- People with medical conditions that may make it unsafe to receive the treatments used in this trial, such as severe infection, active stomach ulcers, blood clotting disorders, connective tissue disease, or conditions affecting bone marrow
- People experiencing significant nerve damage in their hands or feet (peripheral neuropathy above grade 2 on a standard medical scale)
- People with a known severe allergic reaction to any of the drugs used in this study
- People with heart or lung problems, including moderate-to-severe heart failure, chest pain requiring medication, a previous heart attack, significant blood vessel disease, uncontrolled abnormal heart rhythms, or uncontrolled high blood pressure
- People with active hepatitis B or hepatitis C along with abnormal liver function test results, or people known to be HIV positive
- People who are currently pregnant or breastfeeding
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Xuexin He, MD, Seaond Affiliated Hospital, Zhejiang University, School of Medicine
Phone: +86-18329139569
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
This date has passed while the registry still lists the trial as open to participants. Sponsors often update a trial's status without revising its projected end date, so it may well still be recruiting — but the record is out of date in at least one respect. Check with the study contact before relying on either.
Primary endpoints
Disease-free Survival
Can't join this trial?
Data last synced from ClinicalTrials.gov: 13 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.