Heart Disease Trial, Recruiting

Written by an AI model from the ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• You must be an adult (18 years or older)
• You must have had heart surgery using a heart-lung bypass machine more than 24 hours ago, and have had your breathing tube removed for at least 6 hours
• You must have had a weak heart (with the heart pumping less than 40% of its capacity) before your surgery
• You must have special monitoring lines in place — one in the lung artery and one in the wrist artery — that are already being used as part of your care
• You must currently be receiving standard oxygen through a mask or tube, with no increase in oxygen flow needed in the last 30 minutes, and your oxygen levels must be stable (92% or above)
• Your blood pressure, heart function measurements, and lung pressure must have been stable for the last 30 minutes, with no recent increases in heart-supporting medications
• Your oxygen flow rate must be 6 litres per minute or less
• If you are a woman who could become pregnant, you must have a negative pregnancy test at the time of joining
• You must have read and understood the information about the trial and signed a consent form
• You must be covered by a social security (health insurance) scheme

Who may not be able to join:

• You have a medical reason why you cannot use non-invasive breathing support or high-flow oxygen therapy (confirm with trial site)
• You currently have a breathing tube in your throat or a surgical airway opening in your neck
• Your kidneys are failing and you are on dialysis or a blood-filtering machine
• Your blood pressure or heart function is dangerously low, or you require high doses of certain heart-supporting medications (confirm with trial site)
• You are showing signs of serious breathing difficulty, such as breathing very fast, struggling to breathe, or having low oxygen levels
• You have a serious long-term lung or breathing disease
• You already use a breathing support machine (NIV or CPAP) at home
• You have a significant heart valve problem (aortic or mitral valve) that has not been surgically treated (confirm with trial site)
• You have received certain water-removing medications (loop diuretics) by injection within the last 3 hours, or by mouth within the last 6 hours
• You are confused, have altered consciousness, or are showing signs of mental confusion (as measured by specific medical tests)
• You are pregnant, have recently given birth, are breastfeeding, or do not use effective contraception
• You are under a court order, legal guardianship, or have had your personal freedoms restricted by a legal or administrative decision
• You are currently taking part in another clinical trial, or have done so in the last 4 weeks, if that trial could affect this one

Important: Always verify eligibility with the trial site directly before applying.