Hearing Loss Trial, Recruiting NCT04501081 Sponsor: National Institute on Deafness and Other Communication Disorders (NIDCD) Condition: Hearing Loss
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Hearing Loss Trial, Recruiting

NCT04501081
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have inherited hearing loss that runs in their family in a specific pattern (called "autosomal dominant"), ideally confirmed by a genetic test
  • Family members of someone already enrolled in the trial who are known to have this type of inherited hearing loss
  • Family members of someone already enrolled who do not have hearing loss (healthy volunteers)
  • Adults who are able to read, understand, and sign a consent form themselves
  • Children or young people whose parent or guardian is able to read, understand, and sign a consent form on their behalf
  • People between the ages of 3 and 99 years old

Who may not be able to join:

  • People whose hearing loss was caused by something other than genetics, such as an infection, a metabolic condition, an immune disorder, or exposure to certain drugs like cisplatin or aminoglycoside antibiotics
  • People whose hearing loss is linked to a balance problem in the inner ear that was also caused by a non-genetic reason (confirm with trial site)
  • People whose hearing loss is known to be related to a past surgery, such as removal of a type of ear tumour (acoustic neuroma) or a failed ear operation (stapedectomy)
  • People who have a cognitive impairment that prevents them from being able to understand and agree to take part in the study

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 16 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Joshua M Levy, M.D., National Institute on Deafness and Other Communication Disorders (NIDCD)

Phone: (227) 215-4574

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
National Institute on Deafness and Other Communication Disorders (NIDCD)
Registry
ClinicalTrials.gov
Start date
9 February 2021
Est. completion
21 August 2029

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Determine if genome editing could be applied to modify mutations in primary or immortalized cultured fibroblasts from patients with non-syndromic autosomal dominant hearing loss.

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 16 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov