Trial results
AI generated results summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
According to the results reported on ClinicalTrials.gov, this trial enrolled 40 people in total — 19 in one group and 21 in another. All 40 participants completed the trial with no drop-outs. The trial compared two intravenous (drip) treatments given during or after surgery: a normal saline (salt water) solution, which acted as a placebo (an inactive comparison), and a 1,000 mg dose of tranexamic acid, a medication sometimes used to reduce bleeding. Each day for six days after their procedure, participants rated their own bleeding on a scale from 0 (no bleeding at all) to 10 (uncontrolled bleeding). The reported data shows the average self-reported bleeding scores for each group across the six days after the procedure. On day one, the saline group scored 5.03 and the tranexamic acid group scored 4.82. On day two, scores were 4.47 and 3.89 respectively. By day three, both groups reported lower scores — 2.93 for saline and 2.29 for tranexamic acid. On day four, scores were 2.12 and 1.44; on day five, 1.32 and 1.15; and on day six, 1.36 and 0.76. In both groups, the reported scores generally decreased over the six days. No secondary outcome measures were included in the submitted results data. These are the results as reported to ClinicalTrials.gov. They are not medical advice — always discuss what they mean for you with your doctor.
View full results on ClinicalTrials.gov ↗ · Read the linked publication on PubMed (PMID 36608352) ↗
These are the results as reported to ClinicalTrials.gov, not medical advice. Verify independently with the trial site and discuss what they mean for you with your doctor.
Phase 4 Chronic Rhinosinusitis Trial, Completed
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- You are scheduled to have a planned (non-emergency) nose or sinus operation, such as straightening the nasal septum, reducing the turbinate bones inside the nose, or endoscopic sinus surgery
- You are 18 years old or older
- You can speak and understand English
- You are able to give your own informed consent to participate
Who may not be able to join:
- You are under 18 years old
- You are pregnant or think you might become pregnant before your surgery
- You are currently in prison or a correctional facility
- You do not speak English
- You are not a citizen of the country where the trial is being held
- You are not able to give your own consent to take part
- You have a known blood clotting disorder that makes you more likely to develop blood clots (confirm with trial site)
- You are currently using drugs through your nose, such as cocaine
- Your surgery is being done to treat a tumor or growth in your nose or sinuses, or for a condition not listed in the inclusion criteria
- You are already taking part in another research study that would conflict with joining this trial
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Bleeding VAS - POD1; Bleeding VAS - POD2; Bleeding VAS - POD3; Bleeding VAS - POD4; Bleeding VAS - POD5; Bleeding VAS - POD6; Bleeding VAS - POD7; Guaze Saturation VAS Though POD7
Can't join this trial?
Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.