Cardiomyopathy Trial, Recruiting NCT04813159 Sponsor: University of Cape Town Condition: Cardiomyopathy
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Cardiomyopathy Trial, Recruiting

NCT04813159
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

For the main (randomised) part of the trial — patients arriving within 24 hours:

  • You are 18 years old or older and are suspected to have had a serious type of heart attack (called a STEMI), shown by specific changes on a heart tracing (ECG).
  • Your heart attack symptoms began no more than 24 hours ago, as judged by your treating doctor.
  • You are willing and able to sign a consent form agreeing to take part.

For the observation-only part of the trial — patients arriving between 24 and 72 hours:

  • You are 18 years old or older and have signs of a recent serious heart attack (STEMI) that started between 24 and 72 hours ago.
  • Your symptoms, blood test results, heart tracing (ECG), and/or heart scan are all consistent with a recent heart attack.
  • You are willing and able to sign a consent form agreeing to take part.

Who may not be able to join:

For the main (randomised) part of the trial:

  • You are planned to have an emergency procedure to reopen the blocked artery (called primary PCI or angioplasty).
  • Your heart is not pumping well enough to keep your blood pressure stable, and there are signs that your organs (such as kidneys or brain) are being affected as a result.
  • You have a severe active skin condition or burns on both arms.
  • Both of your arms have been amputated.
  • There are signs that one of your arms is not getting enough blood supply (acute limb ischaemia).
  • You have active tissue death (gangrene) affecting any fingers on either hand.
  • You have breast cancer that has spread to nearby lymph nodes on the same side as where the trial procedure (a blood pressure cuff treatment) would be applied.
  • You have blood vessel connections in both arms used for kidney dialysis (bilateral arteriovenous fistulae).
  • You have another serious illness where doctors expect you to survive less than 24 hours.
  • You have a medical reason why you cannot safely receive clot-busting medication (thrombolysis), and your heart attack began less than 12 hours ago (confirm with trial site).

For the observation-only part of the trial:

  • You are unwilling or unable to sign the consent form.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 27 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Mpiko Ntsekhe, PhD, University of Cape Town

Phone: +27732515380

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
University of Cape Town
Registry
ClinicalTrials.gov
Start date
12 January 2022
Est. completion
31 December 2027

Where this trial is recruiting

Kenya Mozambique Senegal 🇿🇦 South Africa Sudan Uganda

Primary endpoints

All-cause death and early post-MI heart failure

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov