Phase 2 Breast Cancer Trial, Recruiting NCT04891068 Sponsor: University of Illinois at Chicago Condition: Breast Cancer
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Phase 2 Breast Cancer Trial, Recruiting

NCT04891068
Recruiting Phase 2

voxsanity.com.au · Eligibility summary from public government registries · 18 August 2026 · not medical advice

Who may and may not be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who may be able to join

  • Adults aged 18 or older at the time of signing consent
  • People with a general health/activity level rated as fully active, restricted in strenuous activity but able to do light work, or able to care for themselves but unable to work (this is measured using a standard scale called ECOG — confirm with trial site)
  • People who have been diagnosed with invasive breast cancer confirmed by biopsy, at an early to locally advanced stage (not yet spread to distant parts of the body)
  • People whose breast cancer falls into one of these categories: triple-negative breast cancer (TNBC); OR hormone receptor-positive breast cancer with certain high-risk features such as HER2-positive status, cancer that has spread to nearby lymph nodes, a high-risk gene expression result, or being progesterone receptor-negative; OR HER2-positive breast cancer
  • People whose blood test results show that the blood, kidneys, and liver are functioning well enough, as tested within 30 days before enrolling
  • People with no evidence that the cancer has spread to distant parts of the body
  • People who have signed a consent form agreeing to take part and allowing their health information to be used
  • Women who could become pregnant must have a negative pregnancy test result before enrolling
  • People who are able to understand and follow the study procedures for the full length of the trial, as assessed by the enrolling doctor

Who may not be able to join

Each point below is a reason the trial team may not be able to accept someone. It is not a list of requirements to meet.

  • People who have already received any cancer treatment for their current breast cancer, including chemotherapy, immunotherapy, targeted therapy, radiation to the breast or nearby lymph nodes, or any experimental treatment
  • People who have breast implants of any kind
  • People who currently have an active infection that requires treatment with medication taken throughout the body (such as antibiotics given by IV or by mouth)
  • People with HIV/AIDS that is not well controlled, or who have an active hepatitis infection
  • People who are currently pregnant or breastfeeding
  • People who have had or currently have another type of cancer that could interfere with assessing the safety or effectiveness of this trial's treatment, as determined by the treating doctor
  • People who have a mental or medical condition that prevents them from giving informed consent or taking part in the trial, unless a legally authorised representative is available to provide consent on their behalf
  • People with other serious health conditions, as determined by the lead study doctor

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 30 July 2026

Contact this trial

Principal Investigator: Vijayakrishna Krishnamurthy Gadi, MD, PhD, University of Illinois at Chicago

Phone: 312-996-1581

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
University of Illinois at Chicago
Registry
ClinicalTrials.gov
Start date
10 January 2022
Est. completion
1 May 2027

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Change in tumor infiltrating lymphocytes (TILs) count in primary tumors from patients with high-risk early stage breast cancer following low-dose azacitidine therapy.

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 30 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov