Liver Cancer Trial, Recruiting (NCT04946773)

Liver Cancer Trial, Recruiting NCT04946773 Sponsor: University of Oxford Condition: Liver Cancer

Printed from Voxsanity (voxsanity.com.au) — NCT04946773 — Data sourced from ClinicalTrials.gov. Verify directly with the trial site before attending. Not medical advice.

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Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

You are willing and able to agree to take part in the study by giving your consent.
You are male or female, aged between 18 and 75 years old.
(Malignancy group only) You have been diagnosed with, or doctors suspect you may have, a cancer affecting the liver or bile ducts.
(Control group only) You have a confirmed long-term, non-cancerous condition affecting the liver or bile ducts.
(For the optional liver tissue sampling procedure only) You are willing to have an ultrasound-guided needle sample taken from your liver.
(For the optional liver tissue sampling procedure only) You have had a scan of your upper abdomen (ultrasound, CT, or MRI) within the last 12 months.
(For the optional liver tissue sampling procedure only) You have had relevant blood tests (a full blood count and clotting tests) done within 30 days before the procedure.

Who may not be able to join:

You are not able to give your own consent to take part.
You are currently pregnant.
The study doctor has any concern about whether it is safe for you to take part, or feels you are not suitable for the study for any reason.
(For the optional liver tissue sampling procedure only) You have serious other health conditions that, in the study doctor's opinion, could make the needle sampling procedure riskier for you.
(For the optional liver tissue sampling procedure only) Your blood clotting results are outside of the acceptable range — specifically, certain clotting measurements are too high or your platelet count is too low (confirm with trial site).
(For the optional liver tissue sampling procedure only) You have a known bleeding disorder, such as haemophilia.
(For the optional liver tissue sampling procedure only) You are currently taking a blood-thinning medication, either as a tablet or injection.
(For the optional liver tissue sampling procedure only) You are currently taking medication that reduces the ability of platelets to clot your blood (sometimes called antiplatelet drugs).
(For the optional liver tissue sampling procedure only) You have a build-up of fluid in your abdomen (a condition known as ascites).

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.

Last synced 2 July 2026

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

GP referral letter

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Voxsanity

Clinical trials and treatments, explained plainly · voxsanity.com.au

Date:

To: My Doctor

Re: Clinical trial enquiry

I am writing to enquire about the following clinical trial which may be relevant to my care:

Trial: NCT04946773

Sponsor: University of Oxford

Phase: Not Applicable

Status: Recruiting

Condition: Liver Cancer

More information: https://clinicaltrials.gov/study/NCT04946773

Eligibility summary (AI generated)

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

You are willing and able to agree to take part in the study by giving your consent.
You are male or female, aged between 18 and 75 years old.
(Malignancy group only) You have been diagnosed with, or doctors suspect you may have, a cancer affecting the liver or bile ducts.
(Control group only) You have a confirmed long-term, non-cancerous condition affecting the liver or bile ducts.
(For the optional liver tissue sampling procedure only) You are willing to have an ultrasound-guided needle sample taken from your liver.
(For the optional liver tissue sampling procedure only) You have had a scan of your upper abdomen (ultrasound, CT, or MRI) within the last 12 months.
(For the optional liver tissue sampling procedure only) You have had relevant blood tests (a full blood count and clotting tests) done within 30 days before the procedure.

Who may not be able to join:

You are not able to give your own consent to take part.
You are currently pregnant.
The study doctor has any concern about whether it is safe for you to take part, or feels you are not suitable for the study for any reason.
(For the optional liver tissue sampling procedure only) You have serious other health conditions that, in the study doctor's opinion, could make the needle sampling procedure riskier for you.
(For the optional liver tissue sampling procedure only) Your blood clotting results are outside of the acceptable range — specifically, certain clotting measurements are too high or your platelet count is too low (confirm with trial site).
(For the optional liver tissue sampling procedure only) You have a known bleeding disorder, such as haemophilia.
(For the optional liver tissue sampling procedure only) You are currently taking a blood-thinning medication, either as a tablet or injection.
(For the optional liver tissue sampling procedure only) You are currently taking medication that reduces the ability of platelets to clot your blood (sometimes called antiplatelet drugs).
(For the optional liver tissue sampling procedure only) You have a build-up of fluid in your abdomen (a condition known as ascites).

Important: Always verify eligibility with the trial site directly before applying.

Access in Australia: A treatment being studied in a clinical trial is generally not yet listed on the PBS. Where a medicine is not approved or not available through a trial, the TGA Special Access Scheme may allow a doctor to access unapproved therapeutic goods for individual patients. See voxsanity.com.au/sas-navigator/ for a plain English explainer.

This information was sourced from ClinicalTrials.gov via Voxsanity (data last synced 2 July 2026). It is not medical advice. Please verify the trial's current status directly with the trial site before acting.

Trial details

Status

Recruiting

Phase

Not Applicable

Sponsor

University of Oxford

Registry

ClinicalTrials.gov

Start date

12 March 2021

Est. completion

31 October 2040

Where this trial is recruiting

🇬🇧 United Kingdom

Primary endpoints

Measurement of intra-hepatic and peripheral blood immune cell numbers in Malignancy Cohort and Control Cohort patients.

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 2 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov