Rheumatoid Arthritis Trial, Recruiting NCT04955899 Sponsor: Galvani Bioelectronics Condition: Rheumatoid Arthritis
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Rheumatoid Arthritis Trial, Recruiting

NCT04955899
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You were diagnosed with rheumatoid arthritis (RA) as an adult, and have had it for at least six months
  • You are between 22 and 75 years old (male or female)
  • Your rheumatoid arthritis is currently active (causing symptoms)
  • Your RA has not responded well enough to at least two biologic or JAK-inhibitor medications (a type of RA treatment)
  • You have stopped taking your previous RA biologic or JAK-inhibitor medications for a required period of time before joining (confirm with trial site)
  • If you are female, you must not be able to become pregnant (confirm with trial site for what this means in your situation)

Who may not be able to join:

  • You are unable to give your informed consent to take part in the trial
  • You have a significant mental health condition or problems with substance abuse
  • You have previously had a surgical procedure that cut a nerve called the vagus nerve (on one or both sides)
  • You currently have, or have a hidden (latent) form of, tuberculosis (TB)
  • You have HIV, active or ongoing hepatitis B or C, or a history of hepatitis B
  • You currently have an electrically powered medical device implanted in your body, such as a pacemaker or a heart defibrillator
  • You have previously had your spleen surgically removed
  • You have recently taken another experimental drug or treatment within a specific time period before surgery (confirm with trial site)
  • You have another inflammatory disease that is not currently under control
  • You have ongoing or repeated infections that the trial doctor considers too risky
  • You have had a cancer diagnosis in the past five years (except certain non-serious skin cancers)
  • You regularly use morphine or oxycodone (strong prescription painkillers)

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 13 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Phone: +44 (0)800 3688514

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Galvani Bioelectronics
Registry
ClinicalTrials.gov
Start date
20 October 2021
Est. completion
1 April 2029

Where this trial is recruiting

🇳🇱 Netherlands 🇬🇧 United Kingdom

Primary endpoints

Safety and tolerability of the Galvani system

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 13 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov