Phase 4 Rheumatoid Arthritis Trial, Recruiting NCT04985435 Sponsor: R.Bos Condition: Rheumatoid Arthritis
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Phase 4 Rheumatoid Arthritis Trial, Recruiting

NCT04985435
Recruiting Phase 4

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You are 18 years of age or older, male or female.
  • You are willing and able to sign a consent form agreeing to take part in the study.
  • You have a good enough understanding of the Dutch language to follow the study requirements.
  • You have been diagnosed with rheumatoid arthritis (RA) as an adult, based on recognised medical criteria.
  • You have had your RA diagnosis for at least 3 months.
  • You have been taking at least one standard RA medication (called a csDMARD) for at least 3 months.
  • Your current standard RA medication has not worked well enough for you, or you have had trouble tolerating it.
  • Your RA is considered moderately to severely active, either as judged by your rheumatologist or based on a specific disease activity score (confirm with trial site).
  • You have been on a stable dose of a standard RA medication (specifically methotrexate, chloroquine, hydroxychloroquine, sulfasalazine, or leflunomide) for at least 4 weeks before the study starts.

Who may not be able to join:

  • You have previously been treated with a biological RA medication or a newer targeted RA medication (including JAK inhibitors).
  • You have another inflammatory joint or rheumatic disease, apart from a condition called secondary Sjögrens syndrome.
  • You have a medical reason why you cannot take either of the two study medications (confirm with trial site).
  • You have latent (inactive) or active tuberculosis.
  • You currently have an active or recurring infection.
  • You have had any cancer in the last 5 years, except for certain successfully treated skin cancers or a localised cervical condition (confirm with trial site).
  • Your liver enzyme levels (ALT or AST) are significantly above the normal range (confirm with trial site).
  • Your kidney function is significantly reduced (confirm with trial site).
  • You are pregnant, planning to become pregnant, or planning to father a child during the study.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 16 July 2026
Phase 4 trials study a drug that has already been approved, monitoring long-term safety and effectiveness in real-world use.

Contact this trial

Principal Investigator: Reinhard Bos, MD PhD, Rheumatology Research Center Northern Netherlands

Phone: 0031(0)582866104

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 4
Sponsor
R.Bos
Registry
ClinicalTrials.gov
Start date
12 May 2021
Est. completion
30 September 2025

Where this trial is recruiting

🇳🇱 Netherlands

Primary endpoints

The proportion of subjects in the first subgroup choosing filgotinib therapy at baseline; Treatment satisfaction at week 24

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 16 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov