Phase 4 Sleep Disorders Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- Children and teenagers between the ages of 5 and 18 (for one part of the study involving xenon gas imaging), or between the ages of 3 and 18 (for other parts of the study)
- Children who still have moderate or severe sleep apnea after having their tonsils and adenoids removed, defined as having more than 5 breathing pauses per hour during sleep
- Children who show signs of an upper airway blockage, such as enlarged tongue tissue at the back of the throat, an unusually large tongue, or a smaller-than-typical jaw
- Children for whom CPAP (a breathing machine used during sleep) has been tried but did not work well enough
- Children whose parents have chosen to pursue surgery rather than trying CPAP
- Children who a surgeon (ear, nose and throat specialist or plastic surgeon) has determined need surgery to treat their sleep apnea
Who may not be able to join:
- Children whose sleep apnea is being successfully managed with CPAP
- Children who have braces or metal rods in their body
- Children who cannot safely receive sedation (calming or sleep medication)
- Children who do not meet the standard safety requirements for having an MRI scan, as determined by the radiology department at the study site (confirm with trial site)
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Alister Bates, PhD, Children's Hospital Medical Center, Cincinnati
Phone: (513) 636-9973
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Predict the surgical option with the most successful outcome with patient-specific validation computational fluid dynamics (CFD) airflow simulations of respiratory upper airways of children with DS and OSA using inhaled Xenon gas phase-contrast MRI.; Measure changes in geometric analysis of airway, airway resistance, and pressure forces with surgical outcome as measured by changes in oAHI (obstructive apnea-hypopnea index)
Can't join this trial?
Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.