Rheumatoid Arthritis Trial, Recruiting NCT05003310 Sponsor: Galvani Bioelectronics Condition: Rheumatoid Arthritis
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Rheumatoid Arthritis Trial, Recruiting

NCT05003310
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have been diagnosed with rheumatoid arthritis (RA) for at least six months, based on recognised 2010 diagnostic guidelines
  • People aged between 22 and 75 years, of any gender
  • People whose rheumatoid arthritis is currently active (meaning symptoms are present and ongoing)
  • People whose RA did not respond well enough to at least two biologic or JAK-inhibitor medications, including at least one TNF inhibitor (a specific type of RA treatment)
  • People who have waited an appropriate amount of time after stopping previous RA biologic or JAK-inhibitor medications before joining the trial (confirm with trial site for specific timeframes)
  • People who are currently taking standard doses of conventional RA medications, or who have a documented history of being unable to use them due to ineffectiveness or side effects

Who may not be able to join:

  • People who are unable to give informed consent to participate
  • People with significant mental health conditions or substance use issues
  • People who have had a surgical procedure that cut or removed the vagus nerve (a nerve running from the brain to the abdomen), on one or both sides
  • People with active or latent (dormant) tuberculosis
  • People with a known HIV infection, current or chronic hepatitis B or C infection, or a previous hepatitis B infection
  • People who test positive for COVID-19 (via PCR test) at the time of screening for this trial
  • People who currently have an electrically active medical device implanted in their body, such as a pacemaker or an implantable heart defibrillator
  • People who have previously had their spleen removed

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 22 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Phone: +1 877 613 9001

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Galvani Bioelectronics
Registry
ClinicalTrials.gov
Start date
19 October 2021
Est. completion
1 July 2027

Where this trial is recruiting

🇳🇱 Netherlands 🇺🇸 United States

Primary endpoints

Incidence of Adverse Events [Safety and Tolerability]; Incidence of Treatment-Emergent Adverse Events [Safety and Tolerability]; Incidence of Treatment-Emergent Adverse Events [Safety and Tolerability]; Incidence of Treatment-Emergent Adverse Events [Safety and Tolerability]

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 22 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov