Heart Disease Trial, Recruiting NCT05027984 Sponsor: Centro per la Lotta Contro l'Infarto - Fondazione Onlus Condition: Heart Disease
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Heart Disease Trial, Recruiting

NCT05027984
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You are 18 years of age or older.
  • You have been diagnosed with acute coronary syndrome (a condition including heart attacks or serious chest pain caused by reduced blood flow to the heart).
  • You have one or more coronary artery blockages that are considered "intermediate" — meaning they are partially, but not fully, blocked (between 40–70% narrowed), with no other severe blockages in the same blood vessel.
  • You are willing to take part and have signed a written consent form approved by the relevant ethics committee.
  • Your doctors expect you to live for more than 3 years.

Who may not be able to join:

  • You are a woman who could become pregnant or are currently breastfeeding.
  • You have significant kidney problems (confirm with trial site for specific levels).
  • You have severe heart failure that causes symptoms during light activity or at rest.
  • You have had a stroke in the last 6 months, or have ever had a bleed inside the brain.
  • You have serious heart valve disease, or valve disease that is likely to need surgery or a procedure during the trial period.
  • The shape or condition of your coronary arteries makes it difficult to get clear imaging of the affected area.
  • The blockage is located in a specific major artery called the left main coronary artery.
  • Your coronary arteries are widely diseased throughout, or you have multiple untreated significant blockages in other vessels.
  • You have previously had a heart attack, bypass surgery, or a stent procedure in the same blood vessel being studied.
  • Your coronary arteries are not suitable for a procedure called PCI (a type of artery-opening treatment).
  • You have other health conditions that could interfere with completing the study.
  • You are planning a major surgery during the trial that would require stopping a specific type of blood-thinning medication.
  • You are currently taking part in another clinical trial for a drug or medical device that could affect this study's results.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 5 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Francesco Prati, MD, Centro per la Lotta con l'Infarto - CLI Foundation

Phone: +39 0677055330

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Centro per la Lotta Contro l'Infarto - Fondazione Onlus
Registry
ClinicalTrials.gov
Start date
30 June 2021
Est. completion
31 March 2026

Where this trial is recruiting

🇬🇷 Greece 🇮🇹 Italy 🇪🇸 Spain 🇨🇭 Switzerland

Primary endpoints

Number of patients with cardiac death or non-fatal spontaneous target-vessel myocardial infarction

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 5 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov