Early Phase 1 Liver Cancer Trial, Recruiting NCT05035108 Sponsor: Sir Run Run Shaw Hospital Condition: Liver Cancer
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Early Phase 1 Liver Cancer Trial, Recruiting

NCT05035108
Recruiting Early Phase 1

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have been diagnosed with liver cancer, stones in the liver's bile ducts (hepatolithiasis), or a non-cancerous liver tumour, and whose doctors have determined that surgery to remove part of the liver is the right treatment
  • People whose liver is functioning at a level doctors classify as "Child A" or "Child B" (a standard medical rating of liver health — confirm with trial site)
  • People whose heart and lung health does not prevent them from having surgery
  • People where the portion of liver expected to remain after surgery is less than 50% of the normal liver size for their body

Who may not be able to join:

  • People in a very advanced stage of illness who are experiencing serious brain complications, such as brain swelling, brain herniation, or signs of bleeding in the brain
  • People with severely low blood oxygen levels that cannot be corrected with treatment (confirm with trial site)
  • People with a condition where the blood's clotting system is not working properly throughout the body (disseminated intravascular coagulation)
  • People who have active bleeding
  • People with an infection that is not under control
  • People with a very low platelet count (the blood cells that help clotting) that cannot be corrected with treatment
  • People who do not have a suitable blood vessel available for dialysis treatment
  • People who test positive for HIV, hepatitis D (HDV), or hepatitis C (HCV)
  • People who have used illicit drugs within the past year
  • People with severe failure of the body's overall circulation system
  • People with a known serious allergy to treatments that may be used, such as plasma, heparin, or protamine
  • People who are pregnant
  • People who have a condition called hepatorenal syndrome, where both the liver and kidneys are affected
  • People with autoimmune liver disease (where the immune system attacks the liver)
  • People with non-alcoholic fatty liver disease or certain inherited liver conditions, including Wilson's disease or alpha-1 antitrypsin deficiency
  • People whose treating doctor believes they are not well enough to tolerate the treatment for any other reason

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
Early Phase 1 studies are small, early exploratory studies that come before the main Phase 1 to 3 testing, so a standard phase success rate does not apply.

Contact this trial

Principal Investigator: Yifan Wang, MD, Sir Run Run Shaw Hospital

Phone: 0086-0571-86006605

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Early Phase 1
Sponsor
Sir Run Run Shaw Hospital
Registry
ClinicalTrials.gov
Start date
5 September 2021
Est. completion
30 November 2030

Where this trial is recruiting

🇨🇳 China

Primary endpoints

The incidence of adverse events (safety and tolerability).

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov