Liver Cancer Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- You are 18 years of age or older
- You have been diagnosed with stage IV colon or rectal cancer that has spread to the liver only, and your doctors are planning surgery to remove part of your liver with the goal of curing you
- Instead of, or in addition to liver surgery, your liver tumours may be treated by burning them away using a needle technique (radiofrequency or microwave ablation); if you have only one liver tumour, three small tissue samples will be taken for research before it is destroyed
- You may be scheduled for a two-stage liver surgery (where the liver is operated on in two separate procedures)
- You may have small spots on your lungs or in your abdomen at the start of the trial, as long as your doctor does not consider these to be cancer that has spread outside the liver
- You may be receiving a chemotherapy plan called FOLFOX, with or without additional cancer drugs (such as Irinotecan or targeted therapies)
- You are willing and able to provide blood samples, tissue samples, and stool samples for research purposes throughout the trial
- Treatment of your original colon or rectal tumour will follow your doctor's standard care plan, which may include radiation therapy for rectal cancer
- You may also receive standard chemotherapy after your surgery, as decided by your doctor
- You are willing to be enrolled in the Exactis Personalized my Treatment patient registry (confirm with trial site)
Who may not be able to join:
- You are currently pregnant or breastfeeding
- You have a hereditary form of colorectal cancer, such as familial adenomatous polyposis (FAP) or Lynch syndrome
- You currently have another type of cancer at the same time
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Simon Turcotte, MD, MSc, CHUM
Phone: 514-890-8000
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Radiological response to pre-operative chemotherapy as assessed by RECIST v1.1; Biochemical response to pre-operative chemotherapy as assessed by plasmatic CEA measurement, change from baseline after 4 cycles of chemotherapy; Pathological response to pre-operative chemotherapy as assessed by Ryan and Rubbia Brandt Tumor Regression Grade (TRG) scores on resected tumors; Tumor response to pre-operative chemotherapy as assessed by change in circulating tumor DNA level, change from baseline; Histopathologic growth pattern as assessed by percent replacement, desmoplastic, and pushing features measu...
Can't join this trial?
Data last synced from ClinicalTrials.gov: 13 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.