Depression and Anxiety Trial, Not Yet Recruiting
voxsanity.com.au · Eligibility summary from public government registries · 18 August 2026 · not medical advice
Who may and may not be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who may be able to join
- People of any gender are eligible.
- People who are being treated as outpatients (not admitted to hospital) are eligible.
- People who are voluntarily choosing to participate and are able to give informed consent are eligible.
- People who have been formally diagnosed with Major Depressive Disorder (MDD) — either a single episode or recurring — confirmed using a standard diagnostic interview are eligible.
- People aged between 18 and 65 years are eligible.
- People whose current depression has not responded well enough to an adequate dose of an antidepressant, or who were unable to tolerate at least two separate antidepressant medications at the minimum required dose or duration, are eligible (confirm with trial site how this is assessed).
- People with a depression severity score of 18 or higher on a standard rating scale called the Hamilton Depression Rating Scale are eligible.
- People who have not had any psychiatric medication increased or newly started in the 4 weeks before the screening appointment are eligible.
- People who are able to follow and attend the required treatment schedule are eligible.
- People who pass the standard safety screening questionnaires for TMS (a type of brain stimulation) and MRI are eligible.
Who may not be able to join
Each point below is a reason the trial team may not be able to accept someone. It is not a list of requirements to meet.
- People who have used substances (such as alcohol or drugs) in the last 3 months may not be eligible.
- People with a serious, unstable physical health condition may not be eligible.
- People who are currently experiencing active thoughts of suicide with intent may not be eligible.
- People who are pregnant may not be eligible.
- People who have ever been diagnosed with a psychotic disorder or bipolar disorder may not be eligible.
- People whose primary diagnosis is considered to be an anxiety disorder or personality disorder — meaning it causes more difficulty than their depression — may not be eligible (this is assessed by a study investigator).
- People who have previously had a full course of electroconvulsive therapy (ECT) that did not help may not be eligible.
- People who have previously received repetitive Transcranial Magnetic Stimulation (rTMS) may not be eligible.
- People with a significant neurological condition, a history of seizures (other than those caused by ECT treatment), or a serious head injury involving more than 5 minutes of unconsciousness may not be eligible.
- People who have metal implants inside or near the head — such as aneurysm clips, shunts, stimulators, cochlear implants, or electrodes — or any other metal objects near the head that cannot be safely removed may not be eligible.
- People currently receiving psychotherapy who have not been in a stable, unchanged treatment for at least 3 months before joining, or who expect changes to their therapy during the study, may not be eligible.
- People with a significant abnormal result on laboratory tests, as judged by a principal investigator, may not be eligible.
- People currently taking more than 2 mg per day of lorazepam (or an equivalent sedative medication), or any amount of anti-seizure medication, may not be eligible, as these can reduce the effectiveness of rTMS.
- People with a sensory impairment that cannot be corrected — for example, not being able to hear well enough to take part in interviews — may not be eligible.
- People whose depression has not responded to more than three adequate medication trials during the current episode may not be eligible.
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
If you need support right now
This page includes language about suicide and self-harm, because that is how the trial's eligibility criteria are written. If reading it has been hard, you do not have to keep going. The services below are free, confidential, and answered by people trained for exactly this.
If you or someone else is in immediate danger, call 000.
- Lifeline — 24/7 crisis support: 13 11 14
- Suicide Call Back Service — 24/7 counselling: 1300 659 467
- 13YARN — 24/7, for Aboriginal and Torres Strait Islander people: 13 92 76
- Beyond Blue — 24/7 mental health support: 1300 22 4636
- Emergency: 000
Outside Australia? The numbers above are Australian and will not work from overseas. Find a Helpline is a free directory of crisis lines in over 130 countries, run by ThroughLine with the International Association for Suicide Prevention. If you are in immediate danger, call your local emergency number.
Voxsanity is not a crisis service, and nothing on this page is medical advice. More Australian services are listed on our support lines page.
Contact this trial
Principal Investigator: Fidel Vila-Rodriguez, M.D., Ph.D., Department of Psychiatry, UBC
Phone: 604-822-7308
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Change from Baseline in Depressive Symptoms using HDRS-17 Scale at Week 10
Can't join this trial?
Data last synced from ClinicalTrials.gov: 10 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.