Phase 4 Cardiomyopathy Trial, Recruiting NCT05180773 Sponsor: Dennis M. McNamara, MD, MS Condition: Cardiomyopathy
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Phase 4 Cardiomyopathy Trial, Recruiting

NCT05180773
Recruiting Phase 4

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have recently been diagnosed with peripartum cardiomyopathy (a type of heart condition that develops around the time of childbirth) for the first time
  • People who have already given birth and are within the first 5 months after delivery
  • People whose heart pumping strength (measured as LVEF) is at or below 40%, confirmed within 4 weeks of agreeing to join the main part of the trial
  • People whose heart pumping strength is at or below 40%, confirmed within 8 weeks of agreeing to join the breastfeeding group of the trial
  • People who are 18 years of age or older

Who may not be able to join:

  • People who have previously been diagnosed with any heart muscle disease, heart valve disease, or a heart condition present from birth — except those who had peripartum cardiomyopathy in the past, fully recovered, and had a documented heart pumping strength above 55% before or early in a pregnancy
  • People with very high blood pressure that is difficult to control (top number above 160 or bottom number above 95) either at the time of joining or at the time their heart function was measured
  • People who are currently breastfeeding after giving birth and plan to keep breastfeeding
  • People with evidence of significant blockages in the arteries that supply the heart (confirm with trial site)
  • People who have previously had a heart transplant
  • People currently using a long-term mechanical heart pump device (LVAD)
  • People currently on a life-support machine that does the work of the heart and lungs (ECMO)
  • People with a current history of alcohol or drug misuse
  • People who have had chemotherapy or radiation treatment to the chest within the past 5 years
  • People showing signs of an active serious bacterial infection in the bloodstream
  • People with medical, social, or mental health conditions that would make it difficult to attend follow-up appointments or comply with the study requirements

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 22 July 2026
Phase 4 trials study a drug that has already been approved, monitoring long-term safety and effectiveness in real-world use.

Contact this trial

Principal Investigator: Dennis McNamara, University of Pittsburgh

Phone: 412-802-3131

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 4
Sponsor
Dennis M. McNamara, MD, MS
Registry
ClinicalTrials.gov
Start date
27 July 2022
Est. completion
30 June 2026

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Left ventricular ejection fraction (LVEF) at 6 months post entry as determined by echocardiography

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 22 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov