Alzheimer's Disease Trial, Not Yet Recruiting NCT05183321 Sponsor: Union Hospital, Tongji Medical College, Huazhong University of Science and Technology Condition: Alzheimer's Disease
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Alzheimer's Disease Trial, Not Yet Recruiting

NCT05183321
Not Yet Recruiting Not Applicable

voxsanity.com.au · Eligibility summary from public government registries · 18 August 2026 · not medical advice

Who may and may not be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who may be able to join

  • The person has completed at least primary school education.
  • The person has been diagnosed with probable Alzheimer's disease dementia based on recognised medical guidelines (NIA-AA criteria).
  • The person has had a brain MRI scan during the screening period that matches an Alzheimer's disease diagnosis (a CT scan may be used instead only if MRI is medically not possible for that person).
  • The person scores 4 or less on a standard test used to help distinguish Alzheimer's disease from other types of dementia (the Modified Hachinski scale).
  • The person scores 15 or higher on a standard memory and thinking test (the MMSE) at screening.
  • People already taking stable doses of common Alzheimer's medications (acetylcholinesterase inhibitors and/or memantine) may be eligible, as long as the dose has not changed in the 90 days before screening and no changes are planned during the study.
  • The person has a primary caregiver who is willing to take responsibility for overseeing treatment and monitoring the person's condition throughout the entire study, as required by the study rules.
  • The person has a body mass index (a measure of weight relative to height) below 38 at screening.

Who may not be able to join

Each point below is a reason the trial team may not be able to accept someone. It is not a list of requirements to meet.

  • The person's brain scan suggests a type of dementia other than Alzheimer's disease.
  • The person has a history of their memory or thinking improving or being restored based on their medical records.
  • The person has a history of, or currently has, a significant mental health condition such as schizophrenia, bipolar disorder, or major depressive disorder that could affect their ability to take part in the study and complete all assessments (note: mild depression or low mood related to Alzheimer's disease does not automatically exclude someone; use of antidepressants or certain anti-seizure medications for non-seizure purposes is allowed if the dose has been stable for at least 60 days before enrolment).
  • The person has a pacemaker (unless it is a newer compatible model), large metal implants, or implanted electronic devices such as cochlear implants, magnetic metal drug pumps, nerve stimulators, diaphragm stimulators, injection pumps, physiological stimulators, or mechanical heart valves.
  • The person has magnetic metal foreign objects or prosthetics in their eye, or magnetic metal joints or ferromagnetic foreign objects anywhere in their body.
  • The person has epilepsy or claustrophobia (fear of enclosed spaces).
  • The person has received antibiotics or dental/gum (periodontal) treatment in the last 6 months.
  • The person has taken aspirin, warfarin, or other blood-thinning (anticoagulant) medications in the last 6 months.
  • The person has any of the following results from blood tests done at screening: a blood clotting disorder; a haemoglobin level of 10 g/dl or below (indicating anaemia); poorly controlled diabetes (HbA1C above 8); or a positive test for HIV, Hepatitis B, or Hepatitis C.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 14 August 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Lili Chen, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

Phone: 0086-027-85726480

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Not Yet Recruiting
Phase
Not Applicable
Sponsor
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Registry
ClinicalTrials.gov
Start date
1 June 2024
Est. completion
31 December 2026

Primary endpoints

Alzheimer's Disease Assessment Scale-Cognitive Subscale 11 (ADAS-Cog 11); ADCS-ADL

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 14 August 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov