Printed from Voxsanity (voxsanity.com.au) — NCT05186116 — Data sourced from ClinicalTrials.gov. Verify directly with the trial site before attending. Not medical advice.
Back to Liver Cancer
Liver Cancer Trial, Recruiting
NCT05186116
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- You are 18 years of age or older
- You have been diagnosed with colon or rectal cancer (inside the abdominal cavity) confirmed by a tissue sample (biopsy)
- Your original tumor meets specific pathology requirements: it was at an early-to-moderate stage, was fully removed with clear margins, does not have certain genetic changes (B-RAF must be normal), and does not have a large mucus-producing component (confirm with trial site)
- Scans (CT, MRI, and PET/CT) show no signs that the cancer has spread outside the liver or come back at the original site
- Your liver tumors cannot be removed by surgery to cure the cancer
- Your cancer responded well to first-line treatment for at least 4 months, OR showed at least stable disease during second-line treatment for at least 4 months
- A specific blood marker for cancer (CEA) has been stable or going down leading up to the liver transplant
- You are in reasonably good general health and able to carry out most daily activities (ECOG score 0–2; confirm with trial site)
- You are willing and able to give informed consent and attend all required treatments and follow-up appointments
Who may not be able to join:
- You have a hereditary bowel cancer condition such as Familial Adenomatous Polyposis (FAP) or Lynch syndrome
- Your cancer has previously spread outside the liver, or the original tumor has come back
- Your original bowel cancer surgery was done only to relieve symptoms, not to fully remove the cancer
- Your cancer is currently getting worse (progressing)
- You have had another cancer in the past 5 years (although certain minor skin cancers and early-stage cervical cancer may be exceptions — confirm with trial site)
- You are currently misusing drugs intravenously or regularly misusing alcohol (you may still be considered if you can show more than 6 months of abstinence)
- You have an active HIV infection
- You have significant psychiatric conditions or a history of not following medical treatment plans
- The trial doctors have any other specific concern about your participation (confirm with trial site)
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Status
Recruiting
Phase
Not Applicable
Sponsor
Azienda Ospedaliero-Universitaria di Modena
Registry
ClinicalTrials.gov
Start date
1 January 2022
Est. completion
1 January 2027
Where this trial is recruiting
🇮🇹 Italy
Primary endpoints
Overall survival; Disease free survival
Can't join this trial?
Data last synced from ClinicalTrials.gov: 5 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.
Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.