Chronic Rhinosinusitis Trial, Recruiting NCT05246267 Sponsor: Montefiore Medical Center Condition: Chronic Rhinosinusitis
Back to Chronic Rhinosinusitis

Chronic Rhinosinusitis Trial, Recruiting

NCT05246267
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You have been diagnosed by a doctor with chronic rhinosinusitis with nasal polyps (a condition where nasal polyps grow in the sinuses), with or without asthma, and you meet the requirements for using the medication Dupilumab as approved by the FDA.
  • You are 18 years of age or older.
  • You are willing to give your consent to take part in the study.
  • You have insurance that covers the medication Dupilumab, or you are able to get coverage through the "Dupixent MyWay Program" (a patient support program).

Who may not be able to join:

  • You are under 18 years old.
  • You have or are suspected of having a fungal sinus infection called allergic fungal rhinosinusitis.
  • You have or are suspected of having cystic fibrosis.
  • Your insurance has denied coverage for Dupilumab and you were also unable to get coverage through the "Dupixent MyWay Program."
  • You have taken a short course of steroid medication (such as prednisone) in the last 30 days — however, if you take a low regular daily dose of prednisone (20 mg or less per day), you may still be eligible (confirm with trial site).
  • You have taken a different biologic medication (a type of specialist drug) in the last 3 months.
  • You have been diagnosed with a condition called EGPA, also known as Churg-Strauss Syndrome (a rare inflammatory condition).
  • You are currently pregnant.
  • You have a type of non-cancerous growth in the nose called an inverted papilloma.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Golda Hudes, MD, Montefiore Medical Center

Phone: 866-633-8255

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Montefiore Medical Center
Registry
ClinicalTrials.gov
Start date
15 February 2022
Est. completion
1 June 2026

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Change in Sinonasal outcome test (SNOT-22) score, scale 0-110, higher is worse outcome; Change in University of Pennsylvania Smell Identification Test (UPSIT) scores, scale 0-40, lower is worse outcome values; Change in nasal peak flow (NPF) value (L/min)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov