Depression and Anxiety Trial, Not Yet Recruiting NCT05396989 Sponsor: Central South University Condition: Depression and Anxiety
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Depression and Anxiety Trial, Not Yet Recruiting

NCT05396989
Not Yet Recruiting Not Applicable

voxsanity.com.au · Eligibility summary from public government registries · 18 August 2026 · not medical advice

Who may and may not be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who may be able to join

  • People who have been diagnosed with a depressive disorder according to standard psychiatric diagnostic guidelines (DSM-5).
  • People between the ages of 18 and 60, of any gender, who have at least one guardian available to check in on them for 2 months.
  • People who are willing to give their informed consent (and whose guardian is also willing to sign the consent forms), and who are able to attend planned visits and complete required tests and study procedures.
  • People who do not expect to move home, have transport difficulties, or have trouble accessing medical care during the study period.
  • People who have adequate sight and hearing to complete the examinations required for the study.

Who may not be able to join

Each point below is a reason the trial team may not be able to accept someone. It is not a list of requirements to meet.

  • People who have any other medical condition that affects reproductive hormone function, or who misuse alcohol or psychoactive substances.
  • People with severe physical disabilities that would prevent them from attending follow-up appointments.
  • People who have been diagnosed with, or have a history of, other serious psychiatric conditions, intellectual disability, dementia, or severe problems with thinking and memory, as defined by standard diagnostic guidelines (DSM-5).
  • People who have a current or past serious physical illness, neurological condition, or brain injury that affects the structure or function of the brain.
  • People who are currently having thoughts of suicide or who are unwilling to cooperate with the study.
  • People who are pregnant or currently breastfeeding.
  • People who have significant anxiety, as measured by a score of 21 or more on a standard anxiety rating scale (HAMA) (confirm with trial site).

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 29 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

If you need support right now

This page includes language about suicide and self-harm, because that is how the trial's eligibility criteria are written. If reading it has been hard, you do not have to keep going. The services below are free, confidential, and answered by people trained for exactly this.

If you or someone else is in immediate danger, call 000.

  • Lifeline — 24/7 crisis support: 13 11 14
  • Suicide Call Back Service — 24/7 counselling: 1300 659 467
  • 13YARN — 24/7, for Aboriginal and Torres Strait Islander people: 13 92 76
  • Beyond Blue — 24/7 mental health support: 1300 22 4636
  • Emergency: 000

Outside Australia? The numbers above are Australian and will not work from overseas. Find a Helpline is a free directory of crisis lines in over 130 countries, run by ThroughLine with the International Association for Suicide Prevention. If you are in immediate danger, call your local emergency number.

Voxsanity is not a crisis service, and nothing on this page is medical advice. More Australian services are listed on our support lines page.

Contact this trial

Phone: +8615874149855

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Not Yet Recruiting
Phase
Not Applicable
Sponsor
Central South University
Registry
ClinicalTrials.gov
Start date
6 May 2024
Est. completion
28 May 2028

Where this trial is recruiting

🇨🇳 China

Primary endpoints

Change in Hamilton Depression Scale (HAMD-17); Change in Pittsburgh Sleep Quality Scale (PSQI); Changes in Beck Suicidal Scale Inventory (BSI); Changes in selective attention through eye-tracking task.; Changes in cerebral blood flow of left DLPFC through Near Infrared Spectroscopy (fNIRS)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 29 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov