Phase 4 Heart Disease Trial, Recruiting NCT05410925 Sponsor: The First Affiliated Hospital with Nanjing Medical University Condition: Heart Disease
Back to Heart Disease

Phase 4 Heart Disease Trial, Recruiting

NCT05410925
Recruiting Phase 4

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People aged 18 to 75 years who weigh at least 45 kg
  • People who have been diagnosed with a specific type of heart attack (STEMI), where chest pain caused by reduced blood flow to the heart has lasted at least 30 minutes
  • People whose heart attack diagnosis is confirmed by a specific pattern on a heart tracing test (ECG) showing abnormal electrical readings across multiple areas of the heart
  • People whose chest pain started no more than 12 hours before being enrolled in the trial
  • People who are expected to undergo an emergency heart procedure (a procedure to open blocked arteries) no sooner than 30 minutes and no later than 120 minutes after enrollment

Who may not be able to join:

  • People who are in a state of severe heart failure causing dangerously low blood pressure (cardiogenic shock)
  • People who have active bleeding or are considered to be at high risk of bleeding, including those with serious eye disease affecting blood vessels, or bleeding in the gut or urinary tract within the past month
  • People who have had a stroke caused by a blood clot, or a temporary stroke-like episode, within the past 6 months
  • People who have ever had a stroke caused by bleeding in the brain
  • People with a known bulge (aneurysm) in a blood vessel in the brain
  • People who have had a serious injury, surgery, or head injury within the past month
  • People suspected of having a tear in the main artery from the heart, or an infection of the heart valves
  • People who have had a medical procedure involving a needle in a location difficult to control for bleeding within the past month (confirm with trial site)
  • People who are currently taking blood-thinning medication (anticoagulants)
  • People with blood pressure that is not well controlled and measures 180/110 mmHg or higher
  • People with severely reduced liver or kidney function, based on blood test results outside acceptable ranges (confirm with trial site)
  • People with a known allergy to the study drug (r-SAK)
  • People who are pregnant, breastfeeding, or planning to become pregnant
  • People who have a history of a fully blocked heart artery that was never treated, a previous heart attack, or a previous open-heart bypass surgery
  • People who have taken certain blood-thinning tablet medications (other than aspirin and ticagrelor, such as clopidogrel, prasugrel, or cilostazol) since their symptoms began
  • People whom the trial doctors consider unsuitable for the trial for other medical reasons

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 19 July 2026
Phase 4 trials study a drug that has already been approved, monitoring long-term safety and effectiveness in real-world use.

Contact this trial

Principal Investigator: Chunjian Li, PHD, The First Affiliated Hospital with Nanjing Medical University

Phone: +86 13701465229

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 4
Registry
ClinicalTrials.gov
Start date
8 April 2023
Est. completion
31 December 2026

Where this trial is recruiting

🇨🇳 China

Primary endpoints

MACE

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 19 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov