Heart Disease Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- Adults aged 18 or older.
- People who have hardened (calcified) blockages in their heart arteries that need to be treated with a procedure to open the artery and place a stent, specifically using a device called a Shockwave catheter.
- People whose calcium deposits in the artery meet specific measurement criteria — either seen on an X-ray image as deposits on both walls of the artery in at least one spot, with a total calcium length of at least 15mm, OR seen on a detailed internal scan showing a large amount of calcium in at least one cross-section of the artery (confirm with trial site for exact measurements).
- People who are able to take two blood-thinning/anti-clotting medications (such as aspirin plus one other) for one year, and then one blood-thinning medication ongoing for life.
- People who are able to give written consent to participate.
- People who are able and willing to attend all required follow-up appointments.
Who may not be able to join:
- People who do not wish to participate in the study.
- People whose calcium deposits are in a section of the artery that is larger than 4mm in diameter.
- People whose affected artery section is in certain bypass graft vessels or at specific connection points of bypass surgery (confirm with trial site).
- People who have an active infection anywhere in the body.
- People who have a known, untreated blood clotting disorder.
- People who have an allergy to the dye used in heart artery imaging that cannot be managed with pre-treatment medication.
- People who are pregnant or breastfeeding.
- People whose life expectancy is less than one year.
- People who are planning to move overseas within one year.
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Primary composite safety endpoint: Target lesion failure (TLF): cardiovascular death; Primary composite safety endpoint: Target lesion failure (TLF): Target-vessel Myocardial infarction (TV-MI); Primary composite safety endpoint: Target lesion failure (TLF): Target lesion revascularization (TLR)
Can't join this trial?
Data last synced from ClinicalTrials.gov: 22 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.