Cardiomyopathy Trial, Recruiting NCT05519046 Sponsor: InCor Heart Institute Condition: Cardiomyopathy
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Cardiomyopathy Trial, Recruiting

NCT05519046
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who are willing and able to sign a consent form before any study procedures begin
  • People aged between 18 and 75 years old (any gender)
  • People who have had a confirmed positive test for Chagas disease within the last two years, shown by at least two different blood tests
  • People whose heart failure symptoms fall into a moderate-to-moderately-severe category (NYHA Class II or III), meaning they experience limitations during physical activity
  • People whose heart is pumping at less than 35% of its normal capacity, as measured by a heart scan
  • People whose heart does not show a specific electrical pattern called "left bundle branch block" (confirm with trial site)
  • People whose heart walls are not beating in a coordinated way, as measured by a specific test called the Yu index (confirm with trial site)
  • People whose heart muscle shows a certain level of reduced function on a specific heart ultrasound measurement called global longitudinal strain (confirm with trial site)

Who may not be able to join:

  • People who are currently in another clinical trial, or who left one less than one year ago (unrelated observation-only studies may be an exception)
  • People who have other heart or blood vessel conditions, including uncontrolled diabetes, or high blood pressure that has already damaged other organs
  • People with significant kidney problems (based on specific blood test results) or liver problems, including cirrhosis, high pressure in the liver's blood vessels, or certain abnormal liver enzyme levels
  • People with moderate or severe long-term lung disease
  • People with nerve damage affecting multiple nerves throughout the body
  • People with an overactive thyroid gland
  • People who currently have, or have had within the last two years, problems with alcohol use
  • People who have been diagnosed with certain serious mental health conditions or addiction to illegal drugs
  • People whose life expectancy is less than one year due to their illness or other health conditions, including those with the most severe level of heart failure (NYHA Class IV)
  • People who are pregnant or currently breastfeeding
  • People who could become pregnant during the study and have not undergone a reliable and permanent form of contraception (confirm with trial site)
  • People who were previously enrolled in this same study and withdrew

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 27 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Phone: +551126615515

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

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Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
InCor Heart Institute
Registry
ClinicalTrials.gov
Start date
25 May 2022
Est. completion
31 December 2027

Where this trial is recruiting

🇧🇷 Brazil

Primary endpoints

QoL Score; QoL Score; GLS; GLS

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov