Sleep Disorders Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
For the first part of the study (Aim 1):
- You are between 18 and 70 years old
- You are able to read and agree to a consent form
For the second part of the study (Aim 2), all of the above, plus:
- You have moderate-to-severe sleep apnea, meaning your breathing stops or is disrupted at least 15 times per hour during sleep
- You have been using a CPAP or similar breathing machine for more than 4 hours per night on at least 70% of nights during a one-week test period
- You have successfully completed all steps from the first part of the study
Who may not be able to join:
For the first part of the study (Aim 1):
- Your Body Mass Index (BMI) is 40 or above (a measure of weight relative to height)
- You have previously had a heart attack, heart bypass surgery or stenting, heart failure, or a stroke
- You have Type 1 or Type 2 diabetes
- You are currently using or have previously used a CPAP machine or a dental/mouth device for sleep apnea
- You take oral steroid medications (such as prednisone)
- You have certain serious or unstable health conditions, such as uncontrolled chest pain, uncontrolled blood pressure, severe lung disease, cancer, or an active mental health condition like major depression
- You have another sleep disorder, or you regularly sleep less than 6 hours per night
- You use extra oxygen at any time, whether awake or asleep
- Your sleep test shows a specific type of sleep apnea caused by the brain (central sleep apnea), a breathing problem related to obesity (obesity hypoventilation syndrome), or an abnormal breathing pattern called Cheyne-Stokes respiration (confirm with trial site)
- Your blood oxygen level while awake and at rest is below 90%
For the second part of the study (Aim 2), all of the above, plus:
- You are a commercial driver, or you have had a car accident or near-accident due to drowsiness in the past 2 years
- Your score on a standard sleepiness questionnaire (Epworth Sleepiness Scale) is 18 or higher, indicating very severe daytime sleepiness
- You are currently taking part in another clinical trial
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Naresh Punjabi, MD, University of Miami
Phone: 305-243-3963
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Whole body lipolysis rate
Can't join this trial?
Data last synced from ClinicalTrials.gov: 5 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.