Liver Cancer Trial, Recruiting NCT05541601 Sponsor: University of Oxford Condition: Liver Cancer
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Liver Cancer Trial, Recruiting

NCT05541601
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • Adults over 18 years old of any gender
  • People who are willing and able to give their informed consent to take part in the study
  • People who have been diagnosed with cirrhosis (scarring of the liver) that is classed as Child-Pugh A or B (a measure of how well the liver is still working), caused by at least one of the following: chronic Hepatitis B, chronic Hepatitis C, alcohol-related liver disease, non-alcoholic fatty liver disease, or haemochromatosis (iron build-up in the liver)
  • The cirrhosis diagnosis must be confirmed by one of the following: a liver biopsy showing advanced scarring, a specialised liver scan or blood test result above a certain threshold (confirm with trial site for exact values), visible signs of liver complications on an endoscopy or scan, or clear imaging evidence of cirrhosis such as a lumpy liver surface and enlarged spleen on ultrasound or CT scan

Who may not be able to join:

  • People who have been diagnosed with liver cancer (hepatocellular carcinoma), either now or at any point in the past
  • People who have had a liver transplant, or who are currently on a waiting list for one
  • People whose cirrhosis is classed as Child-Pugh C (the most severe category of liver function decline)
  • People who, in their treating doctor's view, have another serious health condition likely to be life-limiting within the next 12 months
  • People who, in their treating doctor's view, are not considered suitable for routine liver cancer monitoring (HCC surveillance)

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 22 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

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Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
23 February 2022
Est. completion
1 July 2037

Where this trial is recruiting

🇬🇧 United Kingdom

Primary endpoints

Sensitivity of novel diagnostic approaches for the early diagnosis of HCC in enrolled patients who are diagnosed with HCC by conventional approaches.; Specificity of novel diagnostic approaches for the early diagnosis of HCC in enrolled patients who are diagnosed with HCC by conventional approaches.; Positive/Negative predictive values of novel diagnostic approaches for the early diagnosis of HCC in enrolled patients who are diagnosed with HCC by conventional approaches.

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 22 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov