Phase 2 Heart Disease Trial, Recruiting NCT05604131 Sponsor: Rohan Dharmakumar Condition: Heart Disease
Back to Heart Disease

Phase 2 Heart Disease Trial, Recruiting

NCT05604131
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People aged between 18 and 79 years
  • People who have had a specific type of heart attack called an anterior wall STEMI (a blockage affecting the front wall of the heart)
  • People who have undergone an emergency procedure to open a blocked heart artery (known as a primary PCI, done via a coronary angiogram)

Who may not be able to join:

  • People who have had a previous heart attack, a heart artery procedure (PCI), or open-heart bypass surgery within the past year
  • People with a known history of reduced heart pumping function (the heart pumping less than 40% of its capacity)
  • People who have used an experimental drug or medical device in the 30 days before joining the trial
  • People with a known allergy or medical reason to avoid gadolinium or contrast dye (substances used in certain scans)
  • People with significantly reduced kidney function (confirm with trial site)
  • People who have any reason they cannot safely have a cardiac MRI scan, such as having certain metal implants in their body
  • Women who are pregnant or breastfeeding; women who could become pregnant must have a negative pregnancy test before joining
  • People who weigh more than 140 kg (approximately 309 lbs)
  • People with a low level of a specific type of white blood cell called neutrophils (confirm with trial site)
  • People with a history of chronic liver disease
  • People with significantly elevated liver enzyme levels (both ALT and AST raised to more than twice the normal upper limit)
  • People who have an iron storage condition such as hemochromatosis or thalassemia, or who are already taking medication to remove excess iron from the body
  • People with any other significant health concern that, in the trial doctor's judgment, could make it unsafe to participate or could affect the trial results
  • People whose life expectancy is less than one year due to a non-heart-related illness

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 15 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Keyur P Vora, MD FACP FACC, Medical Imaging Research Institute, Indiana University School of Medicine

Phone: (317) 274-0985

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
Rohan Dharmakumar
Registry
ClinicalTrials.gov
Start date
8 November 2022
Est. completion
31 March 2029

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Treatment Efficacy

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 15 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov