Phase 3 Liver Cancer Trial, Recruiting NCT05608200 Sponsor: Second Affiliated Hospital of Guangzhou Medical University Condition: Liver Cancer
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Phase 3 Liver Cancer Trial, Recruiting

NCT05608200
Recruiting Phase 3

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People diagnosed with advanced liver cancer (hepatocellular carcinoma, or HCC) at a specific advanced stage, confirmed either by a tissue sample or through clinical assessment
  • People whose liver cancer has come back after surgery or a procedure to destroy the tumor (ablation)
  • People who have at least one measurable liver tumor that can be tracked during the trial
  • People whose liver is functioning at a level classified as Child-Pugh class A or B (a measure of liver health — confirm with trial site)
  • People whose general physical health and ability to carry out daily activities is rated at 0 or 1 on a standard scale (meaning fully active or able to carry out light activity)
  • People with a life expectancy of at least 3 months

Who may not be able to join:

  • People whose cancer has blocked the main blood vessel entering the liver (portal vein) on both sides, or the main trunk, without any alternative blood flow pathways
  • People whose cancer has spread into the large vein that carries blood back to the heart (inferior vena cava)
  • People whose cancer has spread to the brain or spinal cord
  • People who have already received certain treatments for their liver cancer, including systemic therapy, immunotherapy, chemoembolisation (TACE), radioembolisation (TARE), arterial embolisation (TAE), hepatic arterial infusion chemotherapy (HAIC), or radiation therapy
  • People who have had an organ or cell transplant in the past
  • People with a history of bleeding from varicose veins in the oesophagus or stomach
  • People with a history of hepatic encephalopathy (a condition where liver disease affects brain function)
  • People whose blood test results show low white blood cell counts or low platelet counts below specified levels
  • People whose blood clotting time is significantly prolonged beyond a certain threshold
  • People with severe dysfunction of the heart, lungs, or kidneys
  • People who have had a cancer other than liver cancer
  • People with active hepatitis B or C infection with virus levels above specified limits (people whose virus levels have dropped below these limits after antiviral treatment may still be considered eligible)

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 27 July 2026
Phase 3: approximately ~65% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Kangshun Zhu, MD, Second Affiliated Hospital of Guangzhou Medical University

Phone: +86-20-34156205

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 3
Sponsor
Second Affiliated Hospital of Guangzhou Medical University
Registry
ClinicalTrials.gov
Start date
2 November 2022
Est. completion
31 October 2026

Where this trial is recruiting

🇨🇳 China

Primary endpoints

Overall survival (OS)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov