Phase 3 Liver Cancer Trial, Recruiting NCT05608213 Sponsor: Second Affiliated Hospital of Guangzhou Medical University Condition: Liver Cancer
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Phase 3 Liver Cancer Trial, Recruiting

NCT05608213
Recruiting Phase 3

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have been diagnosed with hepatocellular carcinoma (liver cancer), confirmed by biopsy, lab testing of cells, or clinical diagnosis by a doctor
  • People whose liver cancer has stopped responding to a procedure called TACE (a treatment that delivers chemotherapy directly to liver tumours), based on specific criteria set by Japan's liver disease medical society (2021)
  • People whose liver cancer has come back after surgery to remove a tumour or after ablation (a procedure that destroys tumour tissue)
  • People who have at least one liver tumour that is large enough to be measured on scans
  • People whose liver is still functioning at a level rated as Child-Pugh class A or B (a measure of liver health used by doctors)
  • People whose general physical health and ability to carry out daily activities is rated 0 or 1 on the ECOG scale (meaning fully active or able to carry out light work)
  • People who are expected to live for at least 3 more months

Who may not be able to join:

  • People whose cancer has spread to areas outside the liver
  • People who have a blood clot or tumour blocking the main blood vessel supplying the liver (portal vein) or both of its main branches
  • People whose cancer has grown into the large vein that carries blood to the heart (vena cava)
  • People who have previously received systemic drug therapy, immunotherapy, chemotherapy delivered through the liver artery (HAIC), or radiation therapy for their liver cancer
  • People who have had an organ or cell transplant in the past
  • People who have had bleeding from swollen veins in the oesophagus or stomach (a complication of liver disease)
  • People who have had a history of hepatic encephalopathy (a condition where a poorly functioning liver causes confusion or brain-related symptoms)
  • People whose platelet count (cells that help blood clot) is below 50×10⁹/L on blood tests
  • People whose blood clotting time is significantly prolonged (prothrombin time extended by 4 seconds or more)
  • People who have serious problems with their heart, lungs, or kidneys
  • People who have had another type of cancer (other than liver cancer) in the past

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 27 July 2026
Phase 3: approximately ~65% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Phone: +86-20-34156205

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

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Trial details

Status
Recruiting
Phase
Phase 3
Sponsor
Second Affiliated Hospital of Guangzhou Medical University
Registry
ClinicalTrials.gov
Start date
2 November 2022
Est. completion
31 October 2026

Where this trial is recruiting

🇨🇳 China

Primary endpoints

Overall survival (OS)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov