Phase 4 Rheumatoid Arthritis Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• You have been diagnosed with Rheumatoid Arthritis (RA) using recognised medical guidelines, AND you have problems with your knee function.
• You meet the 1987 RA classification by having at least 4 of these 7 signs: morning stiffness lasting at least 1 hour (for 6+ weeks); 3 or more swollen joint areas (for 6+ weeks); swelling in the wrist or finger joints (for 6+ weeks); matching swelling on both sides of the body (for 6+ weeks); specific hand X-ray changes; or a positive rheumatoid factor blood test (confirm with trial site).
• Alternatively, you may qualify under 2010 RA guidelines, which use a scoring system based on which joints are affected, certain blood test results, inflammation markers, and how long symptoms have lasted (confirm with trial site).
• OR you have been diagnosed with Osteoarthritis (OA) of the knee, with most-days knee pain in the last month, plus other specific signs such as a grating sound in the knee, morning stiffness lasting 30 minutes or less, being aged 38 or older, or bony enlargement around the knee.
• OR you are a healthy volunteer of a similar age and sex to the patients, who has had a check-up at the hospital involved in the trial.
• You are over 18 years old.
• You are willing to take part and are able to sign a consent form.

Who may not be able to join:

• People who currently have active hepatitis (a liver infection).
• People who currently have active tuberculosis (TB).
• People who currently have an active infection of any kind, or who have been diagnosed with cancer.

Important: Always verify eligibility with the trial site directly before applying.